Duration
15h Th, 15h Pr, 8h AUTR
Number of credits
| Master in biomedicine, research focus | 3 crédits |
Lecturer
François Boemer, Philippe Calmant, Benaïssa Elmoualij, Rosalie Sacheli
Coordinator
Language(s) of instruction
English language
Organisation and examination
Teaching in the second semester
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
The optional course SBIM2034 is a continuation of SBIM2030.
SBIM2030 provides students with the basic principles of clinical biology. Seven specialists present their field of expertise and explain the activities and organisation of their respective laboratory sections.
SBIM2034 focuses more specifically on research, new technologies and recent developments in different fields of clinical biology.
As part of the course, students could spend time in a section of their choice within the Department of Clinical Microbiology and carry out an audit.
Students will write an audit report and present their work orally. The presentation and discussion of the audit report will constitute the final assessment of the course.
Teaching Staff and Course Content
Cécile Meex - 2 hours
Bacteriology: Research Applications
Sébastien Bontems - 2 hours
Molecular Biology and Quality Assurance in Microbiology
Rosalie Sacheli - 2 hours
Role and Missions of National Reference Centres in Clinical Microbiology
Khalid El Moussaoui - 3 hours
The AIDS Reference Laboratory: An Example of Interdisciplinary Collaboration between Infectious Serology, Molecular Biology and Bioinformatics in Clinical Microbiology
Pablo Beckers - 2 hours
Infectious Serology: Research Applications
François Boemer - 2 hours
Diagnosis of Rare Diseases: Complementarity between Metabolomics and Genomics
Philippe Massonnet - 2 hours
Emerging Methods in Clinical Chemistry
In recent years, mass spectrometry has become increasingly important in routine clinical practice. This course presents the main clinical chemistry methods based on this technology.
The first part focuses on liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS), from sample preparation to data analysis and interpretation. These methods will also be compared with more conventional techniques, such as immunoassays, to highlight the advantages and limitations of each approach.
The second part focuses on the development of "omics" approaches, including proteomics, metabolomics and lipidomics. These technologies are increasingly used in preclinical research and offer new opportunities for the identification of biomarkers. The course will conclude with a discussion of the current limitations and future developments of these methods.
Practical Activity - Audit in Clinical Microbiology
Students will carry out an audit in a clinical microbiology section of their choice:
- Bacteriology
- Infectious Serology
- Molecular Biology
- National Reference Centres (NRCs)
- AIDS Reference Laboratory
Learning outcomes of the learning unit
At the end of the course, students will be able to:
- understand recent developments and new technologies in different fields of clinical biology;
- identify the main applications of research in clinical biology and their relevance to diagnosis and patient care;
- understand the organisation and specific activities of different sections of a clinical microbiology laboratory;
- critically analyse the organisation, practices and procedures of a laboratory section;
- carry out an audit in clinical microbiology and identify strengths, possible non-conformities and areas for improvement;
- summarise their observations, write a structured audit report and present the results orally using appropriate scientific and professional language.
Prerequisite knowledge and skills
Students are recommended to have completed MICR0120, MICR0330 and SBIM2030.
The knowledge acquired in these courses provides the necessary background for understanding SBIM2034.
Planned learning activities and teaching methods
The course combines:
- in-person lectures given by specialists in different fields of clinical biology;
- presentations and discussions on recent developments, new technologies and research applications in clinical biology;
- practical experience within a clinical microbiology section;
- an audit carried out in the selected section;
- preparation of an audit report;
- oral presentation and discussion of the audit report.
Mode of delivery (face to face, distance learning, hybrid learning)
Blended learning
Further information:
The course is taught in person and combines theoretical lectures, practical experience within a clinical microbiology section, an audit and an oral presentation of the audit report.
Practical activities are organised in small groups according to the section selected by the student.
Course materials and recommended or required readings
Platform(s) used for course materials:
- eCampus
Further information:
Course materials, reference documents and information required to carry out the audit are available on E-Campus.
Exam(s) in session
Any session
- In-person
written exam ( multiple-choice questionnaire )
Written work / report
Further information:
The course assessment is based on two components:
- a multiple-choice questionnaire (MCQ) in English, using the For Guessing correction method;
- a clinical microbiology audit, including a written report, an oral presentation and a discussion.
Work placement(s)
Organisational remarks and main changes to the course
Contacts
Course Coordinator
Rosalie Sacheli
Department of Clinical Microbiology - CHU de Liège
Email: r.sacheli@chuliege.be
Tel.: +32 (0)4 323 22 98
Secretariat
Stéphanie Wauquier
Email: stephanie.wauquier@chuliege.be
Tel.: +32 (0)4 323 22 90
Department of Clinical Microbiology - CHU de Liège
Tower 6 - Route 656
4000 Liège - Belgium