Duration
Embryology of domestical animals : 26h Th, 6h Pr
Histology of domestical animals I : 8h Th, 16h Pr
Number of credits
| Bachelor in veterinary medicine | 5 crédits |
Lecturer
Embryology of domestical animals : Luc Grobet
Histology of domestical animals I : Luc Grobet, Vinciane Toppets
Coordinator
Language(s) of instruction
French language
Organisation and examination
Teaching in the first semester, review in January
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
Embryology of domestical animals
The course gives access to the essentials for understanding the development of the most common domestic animals, from the zygote stage to birth. Beyond a purely descriptive part, principles of developmental biology and associated technologies are evoked and illustrated by concrete examples.
Histology of domestical animals I
The aim of the Histology I course for domestic animals I is to describe the different healthy tissues of the animal organism. These tissues are assembled into organs, enabling them to perform their functions within the organism.
The Histology I course is integrated into the Embryology course and describes the simple, pseudostratified, stratified, and glandular epithelia mentioned during organogenesis, including their structural, ultrastructural, and functional characteristics.
Learning outcomes of the learning unit
Embryology of domestical animals
The lectures proposed here aim at allowing students to learn about embryonic development, and to get insight into some aspects of modern developmental biology, and associated technologies.
1) Descriptive embryology
The embryonic development from fertilization on until birth is described. The most common species of domestic mammals and birds are considered, and interspecies differences are also pointed out. Relevant connections with anatomical, histological and physiological data are shown.
A) Gametogenesis
Or gametes formation (ova and spermatozoa) from the primordial germ cell stage.
B) Gametes and fertilization
Or the different stages ending up with the zygote formation, which is the first embryonic stage.
C) Cleavage stages
Or the different division steps leading from the zygote (one cell) to the blastocyst stage.
D) Gastrulation
The embryo proper will undergo a clear cell differentiation in three primordial cell layers, from which all body tissues originate.
E) Extraembryonic membranes and placentation
The development of these extra-embryonic tissues allow mechanical protection, feeding, oxygen supply and toxin elimination of the foetus. In mammals, the feto-maternal placental connections are examined in respect with species particularities.
F) Organogenesis
Or development of the organs: we examine:
- Heart and blood vessels
- Nervous system
- Urinary system
- Reproductive organs
- Digestive system and annexes
- Respiratory system
- Body cavities
- Skeleton and joints formation
- Muscles development
- Skin and annexes
2) Modern biology of development, associated techniques and the stem and primordial germ cells revolution
Here are given the essentials of (i) present status of knowledge on stem cells, induced pluripotent cells and primordial germ cells biology and their potential use, and (ii) the most common techniques in use for developmental biology studies. Their potential use as new biotechnological tool in applications such as farm animal improvement, disease resistance, therapeutic proteins production and xenograft supply are discussed based on concrete examples.
A) Transgenesis
Or integration by biotechnological means of (trans)genes in live organisms.
B) Gene targeting
Or precisely directed genome alterations in an organism. The most commonly reported use of gene targeting is gene inactivation by its partial or total elimination (Knock out). This technique can also generate minute insertion or deletions or site-directed integration of transgenes.
C) Cloning
Or genesis of a new organism without sexual reproduction, starting from a more or less differentiated somatic cell.
D) Biology and potential applications of stem and primordial germ cells.
Or description of the origin, particular properties and potential applications of these cells. Somatic cells reprogramming towards pluripotency will be described here.
Histology of domestical animals I
Knowledge
The objective of this theoretical course is to introduce students to the morphological and functional characteristics of different epithelial tissues and to relate the presence and function of different types of junctions to embryological processes.
Know-how
Starting from a purely descriptive approach, students should be able to establish a relationship between the observed morphology and the function of the epithelial cells and epithelia studied.
Soft skills
The availability of virtual histological slides on the e-Campus platform allows students to work in groups, exchange their points of view, develop a certain critical spirit, and encourage mutual assistance.
Prerequisite knowledge and skills
Embryology of domestical animals
The co- and prerequisite teaching units are detailed in the courses program
Histology of domestical animals I
No prerequisites other than a good knowledge of basic biological concepts.
Planned learning activities and teaching methods
Embryology of domestical animals
A theorical course is given in a face-to-face mode. Concerning the practicals, after successful completion of a prerequisite test, every student will assist to three successive practical sessions. They take place in the room of practicals of histology and embryology from october on, which can vary depending on organisation constraints. These lectures aim at deepening and illustrating data which are taught during the theoretical course with help of multimedia supports, examination of microscopic slides of embryos, micro-seminaries and directed analyses of scientific papers. One booklet will be provided to every student within which personal observations will be recorded, and questions relating to the lectures will be answered.
Histology of domestical animals I
Theoretical concepts will be taught in conjunction with embryology during the first semester, as part of the course on embryology and histology of domestic animals.
Practical histology I sessions (TP) are organized during the first semester to complement the theoretical course on embryology and histology.
Objectives of the practical sessions
During the sessions, histological preparations of the various epithelial tissues covered in the theoretical course are made available to students so that they can observe the cellular morphology and tissue organization of the different epithelia.
Organization
Before practical sessions:
- Video clips available on eCampus must be viewed in order to prepare for practical sessions (before or during each session).
- Students then work independently with the help of various resources provided (digitized slides, histology atlas, etc.). Teaching assistants and student monitors are available to guide them through the process.
A passing grade of 70/100 on a prerequisite test is required to attend the first practical work session. This test is available online on eCampus (mandatory formative tests).
During practicals:
The practical sessions are organized in a blended format, alternating between distance learning (via the dedicated eCampus platforms) and face-to-face learning.
Participation in the practical sessions is mandatory.
Repeat students may participate in the practical sessions, but must inform the organizers of their decision to participate or not.
Any non-participation (online), absence, or tardiness (in person) to practical work sessions must be justified before the start of the session by email sent to the secretary of the Department of Morphology-Pathology at the following address: Nathalie.Guillaume@uliege.be).
Any non-participation, absence, or unjustified tardiness will be penalized. If a student has more than one absence from in-person practical sessions that are not justified by a medical certificate during the first quadrimester, he will be barred from taking the exam.
Mode of delivery (face to face, distance learning, hybrid learning)
Embryology of domestical animals
The practicals and theoretical courses are taught in the first semester, the examination takes place during the session of January.
Histology of domestical animals I
Blended learning
Further information:
In-person for theoretical courses on embryology and histology of domestic animals, hybrid for related practical histology work.
Course materials and recommended or required readings
Embryology of domestical animals
The course is available in the ad hoc repertoire of e-campus. The recommended readings and references are also mentioned.
Histology of domestical animals I
Platform(s) used for course materials:
- eCampus
Further information:
Slides and PDF are available in the ad hoc repertoire of e-campus.
A syllabus is available at "l'office des cours"
Slides illustrating the theoretical course are also available to students on e-Campus
Reference book
Applied veterinary histology- William Banks- Third edition-1993 Mosby
Internet sites
http://www.medvet.umontreal.ca/histologie
http://www.chups.jussieu.fr/polys/histo
http://www.udel.edu/Biology/Wags/histopage.htm
Embryology of domestical animals
The evaluation will consist of an integrative interrogation evaluating the subjects taught in Embryology (theoretical course and practical work sessions) and Histology (theoretical course) during the first quadrimester. The proportions of the questions relating to Embryology on the one hand and to Histology on the other hand will approach 3/4 and 1/4, respectively, in order to reflect the relative quantitative importance of these two approaches within the Teaching Unit. In addition, some questions will require reasoning and solutions integrating both disciplines.
The questions will be provided as QCM, QROL and QROC and / or diagrams to annotate.
Histology of domestical animals I
Exam(s) in session
Any session
- In-person
written exam ( multiple-choice questionnaire, open-ended questions )
Out-of-session test(s)
Further information:
Exam(s) during the sessions
The following applies to all sessions.
Regarding the assessment of the theoretical part taught in the embryology and histology course:
The assessment is written during an in-person exam and is included in the first quadrimester's theoretical exam on embryology and histology.
It takes the form of multiple-choice questions and/or open-ended questions.
Additional explanations:
The theoretical assessment will consist of an integrative test evaluating the subjects taught in Embryology (theoretical part and practical sessions) and Histology (theoretical part) during the first semester. The proportion of questions relating to Embryology (3/4) on the one hand and Histology (1/4) on the other will best reflect the relative importance of these two approaches within the Teaching Unit. In addition, some questions will require reasoning and solutions that integrate both approaches.
Questions for both subjects will be written in the form of multiple-choice questions, true/false questions, and/or diagrams to be labeled.
Regarding the assessment of the Practicals:
Certification tests:
Certification exams covering the histology section will be offered online in the form of multiple-choice questions (MCQs) and open short questions. They will be organized in Q1 (histology I) and Q2 (histology II) and will together account for 10% of the overall mark awarded in Q2 for the histology II exam. In Q1, the test will focus on epithelial and glandular tissues.
Formative tests:
During the year, students will take interactive quizzes during practical sessions. The sole purpose of these quizzes is to allow students to evaluate their working methods and understand the level of achievement required at the end of the year. These exercises will not be graded.
Practical exam:
The practical exam will take place in the second quadrimester. The exam will cover the epithelial tissues studied in the first quadrimester, as well as the connective, muscular, vascular, and nervous tissues and blood cells studied in the second quadrimester (Histology II).
It will account for 40% of the overall histology grade.
Work placement(s)
Organisational remarks and main changes to the course
Contacts
Embryology of domestical animals
Professors:
Luc Grobet (coordinator) : lgrobet@uliege.be
Vinciane Toppets : vtoppets@uliege.be
Assistants:
Benoit Vandenhove: B.Vandenhove@uliege.be
Marine Levoz: marine.levoz@uliege.be
Phone : +32 4 366 40 82
Administrative assistant (absences and certificates):
Nathalie Guillaume:
Nathalie.Guillaume@uliege.be
Phone : +32 4 366 40 75 (secretariat)
Histology of domestical animals I
Professors:
Luc Grobet (coordinator) : lgrobet@uliege.be
Vinciane Toppets : vtoppets@uliege.be
Assistants:
Marine Levoz: marine.levoz@uliege.be
Benoit Vandenhove: B.Vandenhove@uliege.be
Phone : +32 4 366 40 82
Administrative assistant (absences and certificates):
Nathalie Guillaume:
Nathalie.Guillaume@uliege.be
Phone : +32 4 366 40 75 (secretariat)