Duration
32h Pr
Number of credits
Lecturer
Brigitte Evrard, Marianne Fillet, Pierre Francotte, Michel Frederich, Anna Lechanteur, Allison Ledoux, Géraldine Piel, Anne-Catherine Servais, Eric Ziemons
Coordinator
Language(s) of instruction
French language
Organisation and examination
Teaching in the second semester
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
The integrated practical work includes 5 pharmaceutical fields: analytical pharmaceutical chemistry, analytical chemistry, medicinal chemistry, pharmacognosy and pharmaceutical technology. During this integrated practical work, the students will synthesize a chiral active compound and characterize it (particles size, nuclear magnetic resonance, enantiomeric purity using capillary electrophoresis). They will also produce pharmaceutical dosage forms containing synthetic or natural active substances (paracetamol tablets, capsules of passionflower herb dry extract). These pharmaceutical dosage forms will then be characterized using pharmaceutical technical procedures (friability, disintegration, resistance to crushing, dissolution test, ...) as well as different analytical methods in order to determine their qualitative and quantitative content (TLC, HPLC, GC, Raman and near-infrared spectroscopy).
Learning outcomes of the learning unit
- To offer the students a global view of a drug, from raw materials to finished products
- To increase students awareness of their future responsibilities as health professionals on the quality of the drugs they will dispense
Prerequisite knowledge and skills
- Drug Analysis (PHAR0344-3)
- Pharmaceutical analytical chemistry (CHIM0320-3, CHIM9332-1 and CHIM0330-3)
- Practical works - Pharmaceutical analytical chemistry (CHIM0321-3 et CHIM9333-1)
- Medicinal chemistry (CHIM0332-2 and CHIM0333-2)
- Pharmacognosy (PHAR0331-3 and PHAR0332-2)
- Pharmaceutical technology and biopharmacy (PHAR0343-3)
Planned learning activities and teaching methods
/
Mode of delivery (face to face, distance learning, hybrid learning)
Face-to-face course
Further information:
The integrated practical work will be organized on 6 consecutive days.
Attendance during practical work is mandatory. In case of justified non-attendance leading to an attendance rate below 90%, the teachers reserve the right to take any action they judge necessary in order to allow the students to catch up the session(s).
Course materials and recommended or required readings
Platform(s) used for course materials:
- eCampus
Further information:
Written notes will be available on eCampus.
Written work / report
Out-of-session test(s)
Further information:
First session
30% of the final grade: test on understanding of the integrated practical works
70% of the final grade: report compiling the results obtained for each module
Second session
Depending on the modules, either the students will receive raw experimental data on the basis of which they will write a report compiling data handling and the answers to thought questions, or they will carry out the module again (experimental work and report).
Work placement(s)
Organisational remarks and main changes to the course
/
Contacts
Anne-Catherine Servais, Chargé de cours
acservais@uliege.be