2020-2021 / PHAR0370-1

Pharmacokinetics

Duration

15h Th, 5h QA Sess.

Number of credits

 Bachelor in pharmacy2 crédits 

Lecturer

Raphaël Denooz, Géraldine Piel

Coordinator

Géraldine Piel

Language(s) of instruction

French language

Organisation and examination

Teaching in the second semester

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

A. Tools and concepts of biopharmaceuticals and pharmacokinetics (Partim Prof G. Piel)
1. Introduction 2. Absorption 3. Distribution 4. Elimination 5. Plasma profile changes depending on the route of administration: pharmacokinetic calculations ... 6. Nonlinear pharmacokinetics 7. Notions of bioequivalence


B. Tools and concepts of therapeutic drug monitoring (Partim Prof R. Denooz)
1. The goals of TDM
2. Which drugs can be monitored?
3. Which patients is it necessary to monitor ?
4.Interpretation of the results and drug doses adaptation

Learning outcomes of the learning unit

The objective of this course is the acquisition of the basic notions of pharmacokinetics necessary for the good use of drugs. The purpose to be reached is the prescription of every medicine to the posology which insures the best efficiency with minimum unwanted effects. The course is illustrated by several examples aiming at a good understanding of the pharmacokinetic section of the scientific leaflet of specialities as well as by the realization of practical exercises.

Prerequisite knowledge and skills

Planned learning activities and teaching methods

For teaching methods, see section below
Learning activities are proposed in the form of exercises

Mode of delivery (face to face, distance learning, hybrid learning)

Depending on the sanitary conditions in Q5, the course will be given face-to-face or in line.
If the course is to be given in line, audio PowerPoint files will be made available to the students via eCampus

Organisational adjustments related to the current health context

Recommended or required readings

Power point presentations will be available

Assessment methods and criteria

Below you will find information on the evaluation methods planned for in-person and remote exams as well as those planned for hybrid sessions. Depending on how the health crisis evolves, the chosen method will be communicated to you no later than one month before the start of the exam session.

Any session :

- In-person

written exam ( multiple-choice questionnaire, open-ended questions )

- Remote

written exam

- If evaluation in "hybrid"

preferred in-person


Additional information:

Depending on sanitary conditions,


  • a written exam will be proposed if the students can be welcomed in amphitheatres.
  • an online exam in the form of multiple choice, true or false, numerical answers, .. will be proposed if the students cannot be welcomed in amphitheatres

Work placement(s)

Organizational remarks

When encoding the educational commitments, the health situation remains uncertain for this academic year. Organizational changes are therefore possible during the year. Students will be notified of any changes in due course.

Contacts

Prof. Géraldine PIEL, Laboratory of Pharmaceutical Technology and Biopharmacy Tél : 04/3664308 geraldine.piel@uliege.be
Prof. Raphaël DENOOZ Clinical and Forensic Toxicological laboratory CHU B35 Sart-Tilman, B4000 Liège Tél.04/3667683 or 04/3668816 Fax 04/3668889 e-mail : Raphael.denooz@chuliege.be