Duration
25h Th, 25h Pr
Number of credits
| Master in bio-informatics and modelling (120 ECTS) | 4 crédits |
Lecturer
Coordinator
Language(s) of instruction
French language
Organisation and examination
Teaching in the first semester, review in January
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
Objectives and program:
1) the tools needed for visualization and analysis of biological macromolecules,
2) an overview of protein modeling methods: homology modeling, ab initio modeling, proteins and ligands, docking methods, etc ...
The course will cover
- a reminder of the protein structure (if necessary ...),
- an introduction to the Protein Data Bank and description of a PDB file,
- an introduction to the Pymol visualization program and TPs on its use,
- the use of 3D structural analysis software (deepview software, PDBePISA)
- modeling by homology - Introduction to the Yasara and TP program on its use
- Protein-Ligand interactions - Introduction to AUTODOCK software
Learning outcomes of the learning unit
Prerequisite knowledge and skills
Planned learning activities and teaching methods
The use of the different software discussed requires the use of a laptop.
Mode of delivery (face to face, distance learning, hybrid learning)
Face to face
Organisational adjustments related to the current health context
Recommended or required readings
Power points Softwares access
Assessment methods and criteria
Below you will find information on the evaluation methods planned for in-person and remote exams as well as those planned for hybrid sessions. Depending on how the health crisis evolves, the chosen method will be communicated to you no later than one month before the start of the exam session.
Any session :
- In-person
written exam
- Remote
written work
- If evaluation in "hybrid"
preferred remote
Additional information:
The examination will consist in the realization of a work and report based on the study of a practical case whose title will be given beforehand.
Work placement(s)
Organizational remarks
25 lessons of 2 hours, at the rate of 2 lessons / week of weeks S1 to S13.
Contacts
Paulette Charlier, PhD, Chargé de Cours
Cristallographie des macromolécules biologiques, Centre d'Ingénierie des Protéines, Département des Sciences de la Vie, Université de Liège, Institut de Physique, B5a, B-4000 Liège, Belgium
Tel: +32 (0)4 366 36 19
Fax: +32 (0)4 366 49 54
E-mail : paulette.charlier@uliege.be
http://www.cip.ulg.ac.be
Frédéric Kerff- Tél. 04/366.36.20 - E-mail : fkerff@uliege.be