Duration
24h Th, 24h Pr
Number of credits
| Bachelor in bioengineering | 4 crédits |
Lecturer
Coordinator
Language(s) of instruction
French language
Organisation and examination
Teaching in the second semester
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
Description of the ralation between the different spectrometries.
Quantic theory and Schrödinger equation.
Ultraviolet-visible spectrometry.
Infrared and raman spectrometry.
Nuclear magnetic resonance spectrometry (1H, 13C, 2D).
Mass spectrometry.
Coupled techniques.
Learning outcomes of the learning unit
Understand theoretical basis of spectrometric methods. Apply these techniques to structural analysis of biological molécules. After completing the course the student is expected to - understand phenomenons that govern the different spectrometry : ultra-violet, visible, infrared, raman, nuclear magnetic resonance, mass spectrometry. - read and explain spectra obtained by the different techniques - apply these techniques on corresponding instruments - identify a molecule from its different spectra
Prerequisite knowledge and skills
CHIM9268-1 - General Chemistry CHIM9255-3 - Organic Chemistry CHIM9239-2 - Biological molecules chemistry CHIM9267-1 - Equilibrium Chemistry
Planned learning activities and teaching methods
Theoretical lectures.
Interpretation exercises of spectra obtained by different spectrometers.
The exercises include a brief theoretical reminder with interpretation of the spectra of different chemical functions, spectrometry exercises made by students with the help of the teacher, summary exercises implementing different spectra for the same unknown molecule.
Practical work for techniques of IR, MALDI-TOF, LC-MS, GC-MS and NMR.
Practical work are given by sets of students working in groups. The experiments illustrate and complement the theoretical notions. Writing a report is requested at the end of the sessions. The presence in the laboratory is mandatory. Any absence must be justified by a medical certificate in proper form. Access to the exam will not be granted to students who have unjustified absences from the TPs or who have not submitted a TP report. For security reasons, access to the laboratory is authorized only for Students with a lab coat, their safety glasses and in order of registration. Glasses should be worn when handling. There is no practical work examination as such. However, questions involving laboratory situations and laboratory 'vocabulary' may appear when evaluating for exercises.
Mode of delivery (face-to-face ; distance-learning)
Lectures : 24h Practical Works : 24h (Execises 8h, practical work on devices 16h)
Recommended or required readings
The course notes include some of the literature that refers student to books that can help to better understanding of the material.
Assessment methods and criteria
Students must bring their student Ulg card and their identity card to attend all events, under penalty of being denied access and consideration of the event.
The distribution of evaluations is as follows:
- Written exam:Theory + exercices: 70%
Practicals :30%
Attendance at practical work is mandatory.
Work placement(s)
Organizational remarks
Contacts
Prof. Christian Damblon
Laboratoire de chimie biologique structurale
UR MolSys
Allée du six Aout 11 - Quartier Agora
B4000 -Liège 1 - Belgium
Département de chimie
Université de Liège
tel +32 4 366 3788
C.Damblon@uliege.be
Prof. Loïc Quinton
Laboratory of Mass Spectrometry - Biological Chemistry
MolSys Research Unit
Allée du six Aout 11 - Quartier Agora
B4000 -Liège 1 - Belgium
Tel +32 4 366 3679
loic.quinton@uliege.be
Adaptation of teaching commitments following the COVID-19 pandemic for the May-June 2020 session
Teaching methods implemented : distance-learning
Lectures are recorded on video and are available as PODCAST. The presentation slides are also available. The entire teaching staff remains available to answer questions by email.
Assessment subjects
The assesment topics will consist of that presented in lectures and in podcasts.
Assessment methods
The exam will consist of open questions of understanding of the theory and exercises of structural analysis. The exercises will consist in solving structures from spectra of the UlgSpectra database. The assessment will be made by a written test carried out remotely ("online"). Students will receive the exam questionnaire by email (or e-Campus) according to the schedule defined in CELCAT. On the day of the exam, students will confirm by return e-mail to c.damblon@uliege.be that the exam questionnaire has been received. They will then have 2 hours to answer the exam questionnaire. Two options are possible; either the student responds on a blank sheet of paper in a handwritten manner, or he uses a word processor. Before the time runs out, students must send their response by e-mail (or by e-campus) to the teacher (c.damblon@uliege.be) either as a word file or as a photo file of the JPEG, TIFF or PDF type (photo of the exam copy taken with a mobile phone for example) of their handwritten response. The name of the course and the student number must imperatively be mentioned in the subject of the email. The teacher will confirm by return e-mail that the exam copy has been received. A computer and a stable internet connection will be required to perform the exam in good conditions. For students who have had problems sending answers by email, an oral exam will be organized by videoconference.
Contacts
Sophie Rappe : sophie.rappe@uliege.be
Loïc Quinton : loic.quinton@uliege.be
Christian Damblon : c.damblon@uliege.be
Adaptation of teaching commitments following the COVID-19 pandemic for the Aug-Sept 2020 session
Assessment subjects
Lectures are recorded on video and are available as PODCAST. The presentation slides are also available. The entire teaching staff remains available to answer questions on the forum on e-Campus
The assessment topics will consist of that presented in lectures and in podcasts.
Assessment methods
The exam will consist of open questions of understanding of the theory and exercises of structural analysis. The exercises will consist in solving structures from spectra of the UlgSpectra database.
The assessment will consist of two separate written tests (Theory and Exercise) carried out remotely ("online"). Students will receive by e-mail (or by e-Campus) separate exam, theory and exercise questionnaires according to the schedule defined in CELCAT.
The theoretical part will be sent first and the students will have 30 min to answer it. Students will then have 15 minutes to send their response by email to c.damblon@uliege.be and Sophie.Rappe@uliege.be.
The exercise questionnaire will be made available 45 minutes after the theory. Students will then have 90 minutes to do the exercise and 15 minutes to email their response to c.damblon@uliege.be and Sophie.Rappe@uliege.be.
For the answers: two options are possible; either the student answers on a blank sheet of paper in a handwritten manner, or he uses a word processor. The student ID number must be written on each sheet which must be numbered (x / total number of pages). Before the time runs out, students must send their response by e-mail either as a Word file or as a photo file of the JPEG, TIFF or PDF type (photo of the exam copy taken with a mobile phone or a scanner, for example) of their handwritten response. The ID of the course and the student ID number must be mentioned in the subject line of the email. In order for teachers to confirm that the exam copy has been received, the student must request an acknowledgment when it is sent.
A computer and a stable internet connection will be required to perform the exam in good conditions.
For students who have had problems sending answers by email, an oral exam will be organized by videoconference.
Contacts
Sophie Rappe : sophie.rappe@uliege.be
Loïc Quinton : loic.quinton@uliege.be
Christian Damblon : c.damblon@uliege.be
Items online
Sectroscopic methods, Mass Spectrometry
Molecular structure analysis, mass spectrometry