Duration
32h Th
Number of credits
| Bachelor in medicine | 5 crédits |
Lecturer
Pierre Bonnet, Philippe Kolh, Michelle Nisolle, Pascale Quatresooz, Marc Radermecker
Coordinator
Language(s) of instruction
French language
Organisation and examination
Teaching in the second semester
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
Physiology in reproductive medicine
- Hypothalamo-pituitary axis function
- Ovarian cycle
- Menstrual cycle
- Fecondation and embryonic implantation
- Adapatations and physiological modifications associated to pregnancy
- Normal delivery: foetus and placenta
- The placenta, the cord and the membrans
- Maternal breast feeding
Learning outcomes of the learning unit
- Describe the role of hypothalamus in ovulation induction
- Describe the hypothalamic neuro-endocrine system
- Describe the relations between the hypothalamus and the pituitary gland
- Understand the importance of the pulsatility of GnRH secretion
- Describe the pulsatility of the GnRH during the cycle
- Describe the clinical consequences of continuous administration of GnRH
- Schematize the hypothalamo-pituitary secretions in relation with the ovarian and menstrual cycles
- Knowledge of the external and internal regulation of the hypothalomo-pituitary axis
- Describe the steroidal feedback on the hypothalamo-pituitary axis
- Describe the role of the pituitary hormones on the ovulation induction
- Describe the follicular growth until the ovulation
- Describe the different phases of the ovarian cycle and variations
- Describe endocrine and exocrine functions of the ovary
- Knowledge of the inhibines role on the ovarian cycle
- Knowledge the follicular atresia and the importance
- Describe the bi-cellular theoric of the steroidal ovarian secretion
- Describe the different steps of the steroidal hormones synthesis
- Describe how to determine the ovarian reserve
- Describe the mecanisms responsible of the ovulation
- Precise the role of the corpus luteum
- Compare the peripheric effects of the progesterone and oestrogens
- Explain the consequences of oestrogens exces
- Describe and compare the different phases of the menstrual cycle
- Explain the initiation of the menstruations
- Describe the embryo implantation and trophoblastic invasion
- Describe the relation between the ovarian cycle and the menstrual cycle
- Describe the implantation window and its importance
- Describe the different possibilities to evaluate the clinical impregnation on oestrogens and progesterone
- Explain the importance of the LH-RH test in amenorrhea
- Explain the different possibilities to explore the ovarian function
- Explain the irregular cycles at the puberty and peri-menopausis
- What are the hormonal analysis needed to diagnose the menopausis
- Explain the role of the progesterone test
- Explain the mecanism of the hormonal contraception
- Describe the role of the foeto placental unit in the steroids production
- Explain the hormones producted by the placenta and the role of the human chorionic gonadotrophin (hCG)
- Describe the mecanisms of the delivery
- Describe the lactation mecanism
- Knowledge of the anatomy and histology of the placenta
- Knowledge of the uterine contraction, consequences on the cervix and the dilatation
- Knowledge of the different physiological maternal modifications in relation with the pregnancy
- Knowledge of the steps of the pulmonary maturation and its clinical implication
- Knowledge of the myometrial histology, main receptors on muscular fibers and the physiology of the contraction
- Knowledge of the mammal gland outside and during the pregnancy and the lactation
- Knowledge of the formation of amniotic liquid and its role
- Knowledge of the insuline resistance during pregnancy
- How to detect the gestational diabetis
- Knowledge of the foetal consequences of the hyperglycemia
- Knowledge of the cinetic and the regulations of the prolactin liberation
- Knowledge of the main signs of aneuploidia
- Knowledge of the different types of twin pregnancies
- Knowledge of the mecanism of the placental explusion
- Knowledge of the modifications of the uterus during pregnancy
- Knowledge of the cervical modification during labor
- Pelvic anatomy during pregnancy and delivery
Prerequisite knowledge and skills
- Anatomy of the hypothalamo-pituitary system and of the female genital tract
- Histology of the female genital tract
- Embryology of the female genital tract
Planned learning activities and teaching methods
This Module is multidisciplinar (based on different theoretical courses in different disciplines).
Practical works (MEDE0124 and MEDE0125) and Problem-based seminars (APPR0141) complete the practical and clinical aspects.
Mode of delivery (face-to-face ; distance-learning)
Hybrid course (theoretical aspects in classical classrooms ; some practical aspects are developped within e-learning and small groups sessions).
Ex-Cathedra courses: 8x2 hours
- Hypothalamo-pituitary axis function
- Ovarian cycle
- Menstrual cycle
- Fecondation and embryonic implantation
- Adapatations and physiological modifications associated to pregnancy
- Normal delivery: foetus and placenta
- The placenta, the cord and the membrans
- Maternal breast feeding
Recommended or required readings
Slides and comments are available on e-campus on line course ; books can be obtained at the Ulg Press Shop (complementary, not compulsory).
Assessment methods and criteria
Written exam :QROC and QCM in june and september Oral evaluation: complete evaluation of the genital module knowledge (APPR0141)
Work placement(s)
Organizational remarks
Contacts
Professor Michelle NISOLLE
michelle.nisolle@ulg.ac.be
Secretary:
Barbara DENEUMOSTIER
barbara.deneumostier@chrcitadelle.be
Professor P.BONNET - Anatomie humaine, Tour de Pathologie 3, niveau -1, CHU Sart Tilman, Bât. B23 (Tél.: 04/366.51.57 ; e-mail: P.Bonnet@ulg.ac.be (pour problèmes non relatifs au cours; sinon utiliser le forum "on-line")
Chef de Travaux
Dr Valérie Defaweux Anatomie humaine, Tour de Pathologie 3, niveau -1, CHU Sart Tilman, Bât. B23
Tél.: +32 4 3665174 +32 4 3662858
e-mail: Valerie.Defaweux@ulg.ac.be
Secretary :
Jessica Thys
Tour de Pathologie 2 - Bât. B36 +1
4000 LIEGE
Tél: 04/366.51.91
Fax: 04/366.59.53
Jessica.Thys@ulg.ac.be
MERCI DE COMMUNIQUER VIA LE COURS EN LIGNE ET d'EVITER DE CONTACTER LE SERVICE CLINIQUE
Anatomie Prosecteurs: Madame M. Wouters, Messieurs G.Dessers, A. Botte
Tour de Pathologie 3, niveau -1, CHU Sart Tilman, Bât. B23 (Tél.: 04/366.51.52-3