Duration
30h Th, 56h Pr
Number of credits
| Bachelor in pharmacy | 7 crédits |
Lecturer
Language(s) of instruction
French language
Organisation and examination
Teaching in the first semester, review in January
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
To complete the required theoretical concepts with a view to instrumental analysis in the pharmaceutical field.
To give students the necessary knowledge to use the following methods and skills:
- Introduction to separative techniques (Separation by change of state, distillation, rectification; fundamental chromatographic parameters).
- Thin Layer Chromatography, Gas Chromatography, High-performance Liquid Chromatography and Supercritical Fluid Chromatography.
- Capillary electrophoresis: principal characteristics of CE; Principle of electrophoresis, theory, electrophoretic mobility, electro-osmotic flow, apparatus.
- Preparation of samples: solid phase extraction and extraction of solid matrices (mineralisation, extraction by supercritical CO2).
- Notions of analytical methodology (Chemometrics): Analysis of data and method validation.
Learning outcomes of the learning unit
To build on the required theoretical concepts with a view to instrumental analysis, in particular complete student training in the use of separation methods. To deal with the different aspects connected to the sample handling and the validation of instrument analysis techniques (Analytical methodology).
To contribute to the general education of future pharmacists on a theoretical level in order to enable them to adopt an analytical approach to work. Teaching is centred on fundamental problems and those encountered in the analysis of medicines (Life cycle of analytical methods). To encourage an analytical and critical approach to work.
Prerequisite knowledge and skills
Preparatory chemistry for the biomedical and pharmaceutical sciences. Physical and mathematical bases of biomedical sciences. Introduction to analytical chemistry.
Planned learning activities and teaching methods
Theoretical teaching is supplemented by practical work: 56 hours.
Quantitative analysis. Titration and instrumental methods applied to the quantitative determination of active ingredients.
Mode of delivery (face-to-face ; distance-learning)
Face-to-face.
Classes take place during the first term (Q5).
Time: see the schedule in the vade mecum.
Practical work :
Place: student laboratory, level +4, tower 4 Building. B36.
Time: see the schedule in the vade mecum.
Attendance at practical work is mandatory.
Recommended or required readings
Condensed notes and photocopies of Powerpoint presentations are distributed to the students.
General works (recommended readings):
"Chimie analytique"; Skoog, West, Holler (French edition, 7th Ed) Ed. De Boeck University, 2002.
"Analyse Chimique. Méthodes et techniques instrumentales modernes"; Rouessac, Ed. Dunod, 2000.
"Analytical Chemistry", Kellner, Mermet, Otto, Widmer
Ed. Wiley, 1998.
Assessment methods and criteria
Theoretical work :
A written exam on the subject defined by the professor and scientific staff : written exam.
Oral resit (first session only) in case of an insufficient score at the written exam.
The oral resit is subject to prior registration. Rejection criterion oral exam: too serious deficiency at the written exam.
Practical work :
Written tests. Written exam on the subject matter of the practical work including the obligatory prerequisites (Q4). The marks from the Practical Work are included in the final mark.
Reminder: Attendance at practical work is mandatory. Consequently, in conformity with article 6 of the general exam rules, a level of absenteeism that is too high may result in students being prohibited from sitting the exam.
Work placement(s)
Training possibilities.
Student-teachers: possibilities are available for students interested in teaching analytical chemistry. The tasks involve supervising the practical work.
Research: outside the course and exam periods (on finishing the 2nd year of the Baccalaureat), motivated students may take part in a course in the laboratory (student-researchers). At the end of the course, there is a possibility of doing a PhD in the department.
Organizational remarks
There is a forum on "MyULg" (heading: Study-course) where the students can put their questions about the matter.
Contacts
Philippe Hubert, Laboratory of Analytical Chemistry, Department of Pharmacy, CHU Bât. B36, Quartier Hôpital,avenue Hippocrate 15, 4000 Liège 1
Phone. : 04/366.43.16 (15)
Fax : 04/366.43.17
e-mail: ph.hubert@ulg.ac.be
Hugues Jambo
Phone : +32 4 366.43.19
e-mail : hjambo@ulg.ac.be
Charlotte De Bleye
Tél : +32 4 366.39.79
e-mail : cdebleye@ulg.ac.be
Eric Ziemons
Phone : +32 4 366.98.01
e-mail : eziemons@ulg.ac.be
Sébastien Lhoest
Phone : 04/366.43.23
Fax : 04/366.43.17
e-mail: slhoest@ulg.ac.be
Secretary:
Florence Bonivert
Phone : 04/366.43.16
Fax : 04/366.43.17
e-mail: florence.bonivert@ulg.ac.be