CHIM0717-1 : Microbial processes and interactions

Study Programmes 2016-2017

CHIM0717-1

Microbial processes and interactions

Duration :

48h Th, 36h Pr

Number of credits :

Master in bioengineering : chemistry and bio-industries (120 ECTS)		7

Lecturer :

Frank Delvigne, Patrick Fickers, Philippe Jacques, Marc Ongena, Jean-Claude Twizere

Coordinator :

Patrick Fickers

Language(s) of instruction :

English language

Organisation and examination :

Teaching in the second semester

Units courses prerequisite and corequisite :

Prerequisite or corequisite units are presented within each program

Learning unit contents :

This course focus on theoretical and practical aspects on technologies related to the production of compounds of biotechnological interest (biomass, proteins, metabolites) for agro-food, chemical and biopharmaceutical industries. The course details the different technologies of bioreactor culture, molecular techniques leading to the development of "cell factory" as well as cell-environment interactions.

Learning outcomes of the learning unit :

At the end of this multidisciplinary module, students will be able to integrate the different aspects of the development, implementation, optimization and control of a process of production of a compound of interest in bioreactor. The course also includes dimensioning part (calculation of oxygen transfer capacity, dynamics of microbial growth and production of metabolites, ...) and on the construction of dynamic models of bioprocesses (resolution of first-order differential equations under MatLab).

Prerequisite knowledge and skills :

BIOL2010-1 : Biologie cellulaire
BIOL2013-2 : Microbiologie générale - Patrim 1
BIOL2013-3 : Microbiologie générale - Partim 2
BIOL2015-3 : Biologie moléculaire
BIAA0003-1 : Génie industriel alimentaire et ingénierie agro-alimentaire - 1ère partie
CHIM9241-1 : techniques de séparation et de concentration
MATH2016-1 : mathématique générale et modélisation des systèmes dynamiques

Planned learning activities and teaching methods :

- Bioreactor engineering (F. Delvigne, 12 h Th)
- Metabolic engineering (P. Fickers, P. Jacques, 12 h Th)
- Microbial interaction (M. Ongena, 12 h Th)
- Animal cell culture (JC Twizere , 12 h Th)
- Exercices (F. Delvigne, P. Fickers, P. Jacques, 12 h, )
- Lab (P. Fickers, P. Jacques, M. Ongena, F. Delvigne, 12 h)
- Numerical simulation (F. Delvigne, 12 h, exercices)
Beside ex-cathedra courses, this module includes practical lab work, exercises (simulation on MatLab), seminars (industrials, academics or research centers) and company visits Active. In this course, a pedagogical approach "learning by doing" will also be favored..

Mode of delivery (face-to-face ; distance-learning) :

Lectures
Lab training
Exercices (numerical simulation using MatLab),
Seminars
Company visit
In this course, a pedagogical approach "learning by doing" will also be favored.