Number of credits
|Master in biomedicine (120 ECTS)||2 crédits|
Language(s) of instruction
Organisation and examination
Teaching in the first semester, review in January
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
The main purpose of this course is to provide students with the molecular mechanisms shared by the addictive disorders (neuro-anatomy of the reward circuits of the brain, molecular, genomic and structural adaptation linked to addiction).
We also review the main addictive substances on a pharmacological, epidemiolocal, clinical and theapeutic point of view. Alcohol dependance is more precisely studied under its genetic, clinical and therapeutic specificities.
Learning outcomes of the learning unit
The objective is to give the student a general overview of the common neurobiological mechanisms shared by the main addictions. Key-informations about the main addictive substances is a secondary objective of this course.
Prerequisite knowledge and skills
Planned learning activities and teaching methods
Ex cathedra courses with Powerpoint support.Key articles provided
Mode of delivery (face-to-face ; distance-learning)
Recommended or required readings
Powerpoint presentationKey-articles :
- Bowirrat, A., & Oscar-Berman, M. (2005). Relationship between dopaminergic neurotransmission, alcoholism, and Reward Deficiency syndrome. Am J Med Genet B Neuropsychiatr Genet(1), 29-37.
- De Witte, P., Pinto, E., Ansseau, M., & Verbanck, P. (2003). Alcohol and withdrawal : from animal research to clinical issues. Neurosci Biobehav R(27 ), 189-197.
- Koob, G. F., & Le Moal, M. (1997). Drug Abuse: Hedonic Homeostatic Dysregulation. Science, 278(5335), 52-58.
- Young, R. M., Lawford, B. R., Nutting, A., & Noble, E. P. (2004). Advances in molecular genetics and the prevention and treatment of substance misuse: Implications of association studies of the A1 allele of the D2 dopamine receptor gene. Addictive Behaviors, 29(7), 1275-1294.
- Cooper, S., Robison,A.J., Mazei-Robison,M.S. (2017). Reward circuitry in Addiction. Neurotherapeutics 14(3),687-697
Assessment methods and criteria
Multiple choices questionnaire