2017-2018 / SBIM0462-1

Pharmacology and addiction clinic


10h Th

Number of credits

 Master in biomedicine (120 ECTS)2 crédits 


Emmanuel Pinto

Language(s) of instruction

French language

Organisation and examination

Teaching in the first semester, review in January

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

The main purpose of this course is to provide students with the molecular mechanisms shared by the addictive disorders (neuro-anatomy of the reward circuits of the brain, molecular, genomic and structural adaptation linked to addiction).
We also review the main addictive substances on a pharmacological, epidemiolocal, clinical and theapeutic point of view. Alcohol dependance is more precisely studied under its genetic, clinical and therapeutic specificities.

Learning outcomes of the learning unit

The objective is to give the student a general overview of the common neurobiological mechanisms shared by the main addictions. Key-informations about the main addictive substances is a secondary objective of this course.

Prerequisite knowledge and skills

Planned learning activities and teaching methods

Ex cathedra courses with Powerpoint support.Key articles provided

Mode of delivery (face-to-face ; distance-learning)


Recommended or required readings

Powerpoint presentationKey-articles :

  • Bowirrat, A., & Oscar-Berman, M. (2005). Relationship between dopaminergic neurotransmission, alcoholism, and Reward Deficiency syndrome. Am J Med Genet B Neuropsychiatr Genet(1), 29-37.
  • De Witte, P., Pinto, E., Ansseau, M., & Verbanck, P. (2003). Alcohol and withdrawal : from animal research to clinical issues. Neurosci Biobehav R(27 ), 189-197.
  • Koob, G. F., & Le Moal, M. (1997). Drug Abuse: Hedonic Homeostatic Dysregulation. Science, 278(5335), 52-58.
  • Young, R. M., Lawford, B. R., Nutting, A., & Noble, E. P. (2004). Advances in molecular genetics and the prevention and treatment of substance misuse: Implications of association studies of the A1 allele of the D2 dopamine receptor gene. Addictive Behaviors, 29(7), 1275-1294.
  • Cooper, S., Robison,A.J., Mazei-Robison,M.S. (2017). Reward circuitry in Addiction. Neurotherapeutics 14(3),687-697

Assessment methods and criteria

Multiple choices questionnaire

Work placement(s)

Organizational remarks