Duration
Natural-source raw materials : 20h Pr
Analysis of biological medicinal products and medicinal products in biofluids : 10h Th
Drug design : 10h Th
Industrial pharmaceutical technology : 10h Th
Sterilisation methods : 10h Th
Number of credits
| Master in pharmacy, professional focus in conception and development of medicine - bioanalysis | 5 crédits |
Lecturer
Natural-source raw materials : Michel Frederich, Allison Ledoux
Analysis of biological medicinal products and medicinal products in biofluids : Marianne Fillet
Drug design : Pierre Francotte
Industrial pharmaceutical technology : Brigitte Evrard, Anna Lechanteur
Sterilisation methods : Aurore Napp, Isabelle Roland, Gaëtan Van Haren
Language(s) of instruction
French language
Organisation and examination
Teaching in the second semester
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
Natural-source raw materials
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Drug design
This course covers the different stages of the design and production of biopharmaceuticals, with a particular focus on monoclonal antibodies and novel siRNA-based therapies. It addresses screening techniques, molecular modeling, rational drug design, studies of target interactions, as well as the production of recombinant proteins and the purification of monoclonal antibodies.
Innovative approaches currently being investigated for the development of new medicines will also be discussed.
Industrial pharmaceutical technology
Industrial production of different pharmaceutical forms.
Learning outcomes of the learning unit
Natural-source raw materials
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Drug design
By the end of this course, students will be able to:
1. Explain the key steps involved in the design and production of biopharmaceuticals.
2. Describe the fundamental principles of monoclonal antibodies and siRNA-based therapies.
3. Apply concepts of screening, molecular modeling, and rational drug design to practical examples.
4. Understand the processes of recombinant protein production and monoclonal antibody purification.
5. Critically analyze innovative approaches currently being investigated in drug development.
Industrial pharmaceutical technology
- In-depth study of pharmaceutical formulation and industrial manufacturing processes;
- Familiarization with the industrial manufacturing environment;
- Understanding of the various stages involved in the industrial production of solid oral dosage forms.
Prerequisite knowledge and skills
Natural-source raw materials
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Drug design
This course builds on prior knowledge in organic chemistry, pharmaceutical chemistry, biochemistry, and general pharmacology.
Industrial pharmaceutical technology
Lessons of pharmaceutical technology
Planned learning activities and teaching methods
Natural-source raw materials
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Drug design
Course requiring active student participation.
Industrial pharmaceutical technology
Theoretical lectures will be delivered in a traditional lecture-based format.
Site visits (including the B36 cleanroom facility and a pharmaceutical company) will also be organized to illustrate and contextualize the theoretical concepts covered during the course.
Mode of delivery (face to face, distance learning, hybrid learning)
Natural-source raw materials
Face-to-face course
Further information:
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Drug design
Face-to-face course
Industrial pharmaceutical technology
Face-to-face course
Course materials and recommended or required readings
Natural-source raw materials
Platform(s) used for course materials:
- eCampus
- MyULiège
Further information:
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Drug design
Platform(s) used for course materials:
- eCampus
Industrial pharmaceutical technology
Platform(s) used for course materials:
- eCampus
Natural-source raw materials
Exam(s) in session
Any session
- In-person
written exam ( open-ended questions )
Written work / report
Continuous assessment
Further information:
Exam(s) in session
Any session
- In-person
written exam
Other : Practical exam and written questions
Drug design
Exam(s) in session
Any session
- In-person
written exam ( multiple-choice questionnaire, open-ended questions )
Industrial pharmaceutical technology
Exam(s) in session
Any session
- In-person
written exam ( open-ended questions )
Work placement(s)
Drug design
Information on internship opportunities within the laboratory will be provided to interested students.
Organisational remarks and main changes to the course
Contacts
Natural-source raw materials
Michel FREDERICH, CARLA HAMANN et Allison LEDOUX
Drug design
Pierre.Francotte@uliege.be
Université de Liège | Fac. de Médecine
B36 niv.+5 | Lab. de Chimie Pharmaceutique (CIRM)
Quartier Hôpital | Av. Hippocrate 15 | B-4000 Liège, Belgium
Industrial pharmaceutical technology
Anna Lechanteur, professeure associée
anna.lechanteur@uliege.be