Duration
40h Th, 26h QA Sess.
Number of credits
| Bachelor in pharmacy | 8 crédits |
Lecturer
Language(s) of instruction
French language
Organisation and examination
Teaching in the second semester
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
The course consists of three modules.
The first module aims to review the various concepts of general chemistry necessary to engage in the course and establish a common language. It includes two chapters:
I.1/ From atom to molecule, electronic aspects.
I.2/ Structure representations.
The second module focuses on the central concepts of organic chemistry, which allow for a systematic description of organic transformations covered in the third module. It includes six chapters:
II.1/ Functions & nomenclature.
II.2/ Electron movements: follow the arrows!
II.3/ Basics of organic synthesis.
II.4/ Reaction classification.
II.5/ Acid/base & consequences.
II.6/ Stereoisomerism.
Finally, the third module primarily reviews the main functional group transformations. This module then addresses general concepts such as retrosynthesis, green chemistry, catalysis, and techniques for identifying organic products. The memorization effort in Module III is reduced if the concepts from Modules I and II have been properly understood. To encourage students in their efforts, in addition to review sessions, two tests are scheduled (see below).
III.1/ Alkenes.
III.2/ Halogenated derivatives.
III.3/ Alkynes.
III.4/ Alcohols and phenols.
III.5/ Ethers and thioethers.
III.6/ Aromatic compounds.
III.7/ Amines.
III.8/ Aldehydes and ketones.
III.9/ Carboxylic acids and their derivatives.
III.10/ Radical synthesis.
III.11/ Synthesis & retrosynthesis.
III.12/ Green chemistry.
III.13/ Catalysis.
III.14/ Techniques for identifying organic products.
Learning outcomes of the learning unit
At the end of this teaching unit, you will be able to:
- Name organic compounds (either by their common names or using IUPAC nomenclature).
- Convert a compound's name into its structural formula.
- Draw structures according to conventions (structural formula, three-dimensional aspects).
- Determine theoretical results of elemental analysis.
- Identify functional groups; among these, identify functions with acid/base properties.
- Indicate expected pKa values for functions with acid/base properties.
- Identify aromatic structures.
- Explain the solubility, extractability, and reactivity of a compound based on its structure.
- Infer the physicochemical properties of a compound from its structure.
- Classify homologous reagents by acidity/basicity/nucleophilicity/reactivity.
- Use ChemDraw to correctly communicate chemical structures.
- Calculate the quantities of reagents and yields obtained during reactions, considering the concept of significant figures.
- Distinguish isomers. For optical isomerism, assign the absolute configuration of asymmetric carbon atoms.
- Search for chemical information using specialized research tools.
- Justify the steps of a procedure.
- Predict the products formed and complete incomplete reaction schemes.
- Propose the probable mechanism of a reaction among those covered in the course.
- Justify the steps constituting a reaction scheme.
Prerequisite knowledge and skills
General Chemistry (Q1)
Planned learning activities and teaching methods
The course includes "ex cathedra" lectures, review sessions (+eCampus).
Thirteen 2-hour review sessions are planned. These sessions aim to help students master the material through problem-solving. The in-person sessions are supplemented each week by online tests on eCampus (formative, non-certifying assessment).
During the review sessions, several exercises are first solved and explained in detail by the instructors. Then, students solve problems on their own with the assistance of the instructors.
Mode of delivery (face to face, distance learning, hybrid learning)
Face-to-face course
Further information:
The theoretical course (40 hours) is conducted in person.
At the beginning of the semester, two groups are created on eCampus for the review sessions: each student selects their group, taking into account any scheduling conflicts, and commits not to change groups during the semester.
It is important to adhere to the organization to ensure that these review sessions run efficiently.
The exercises covered in the review sessions will be made available before each session, with emphasis on the exercises that will be solved/explained by the instructors (the exercises will be the same for both groups).
Course materials and recommended or required readings
Platform(s) used for course materials:
- eCampus
Further information:
**Reference Book:** "Organic Chemistry, 2nd edition" by Paula Yurkanis Bruice is not essential but can be a useful companion. It is available new at Pax for 47 euros, second-hand (with some searching), and in the library (with some searching).
Exam(s) in session
Any session
- In-person
written exam ( multiple-choice questionnaire, open-ended questions )
Further information:
The examination is written and takes place in two stages.
At the beginning of the examination session, a written examination assesses fundamental concepts. These concepts constitute the essential foundations of the discipline, much like the alphabet when learning a new language: without mastering them, it is impossible to build upon and properly understand subsequent material. Students who obtain at least 50% of the marks allocated to this written examination will be admitted to the second part of the assessment, held later during the examination session. This second part assesses more advanced knowledge and skills, which presuppose mastery of the fundamental concepts.
The first part of the examination accounts for 20% of the examination mark, and the second part for 80%.
Students who do not attain the 50% threshold in the first part of the examination will not be admitted to the second part. In that case, the final examination mark will be based solely on the marks obtained in the first part. The final mark is therefore capped, reflecting the fact that insufficient mastery of the fundamentals prevents a valid assessment of more advanced skills.
Two in-course tests are scheduled during the semester. The first is intended to assess students' knowledge of the prerequisites and of the material covered during the first five lectures and the first three tutorial sessions. The second test, held in April, focuses on the material covered during the first fifteen lectures and addressed in the first seven tutorial sessions.
The assessments included in the final mark, with their respective weighting, are as follows: first in-course test [7%] - second in-course test [15%] - examination [78%].
Except in exceptional circumstances, missed in-course tests - whether supported by a medical certificate or not - cannot be retaken and will receive a mark of 0/20.
Each assessment will be completed on the forms provided.
Each student is responsible for ensuring that their examination paper is properly identified. Papers that are not identified, or are incorrectly identified - whether with regard to the student's identity or the version of the questionnaire - will not be marked and will receive a mark of 0/20. During examinations, each student must bring a blue or black ballpoint pen, correction tape, and a non-programmable calculator. No exchange of materials between students will be permitted. Sheets of paper are not allowed. Mobile phones, smartwatches, and other electronic devices must be switched off and placed in a bag.
Work placement(s)
Later in their studies, interested students can engage in research work (as student researchers or during internships).
Organisational remarks and main changes to the course
**Course in French.**
It is important to arrive on time for lectures, review sessions, and lab sessions. Latecomers disrupt the smooth running of the sessions and will have to wait for a break to enter.
If you have questions about the material, please note that email is not suitable, as explanations often require diagrams, which takes a lot of time to respond to a single student. It is preferable to ask your questions via the forum. A forum on eCampus is set up for you to ask questions about the material and to facilitate student collaboration. You are strongly encouraged to use this forum as all students benefit from the provided answers; the forum will be moderated by the instructors every three days. Alternatively, your questions can be asked in person (at the end of a class, during a break, in review sessions, or during lab sessions).
Emails sent to a member of the team must include the following elements: last name, first name, student ID, course concerned, and specific information about the request. Additionally, the subject of the email must mention the course code.
Contacts
Pierre.Francotte@uliege.be
Université de Liège | Fac. de Médecine
B36 niv.+5 | Lab. de Chimie Pharmaceutique (CIRM)
Quartier Hôpital | Av. Hippocrate 15 | B-4000 Liège, Belgium
Secretariat: Lindsay.Louveau@uliege.be