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2026-2027 / CHIM0716-1

From gene to protein

Duration

12h Th, 24h Pr, 12h AUTR

Number of credits

 Master in bioengineering: chemistry and bio-industries, professional focus6 crédits 

Lecturer

Magali Deleu, Patrick Fickers, Malik Hamaïdia, Sébastien Massart, Martine Schroyen, Luc Willems

Coordinator

Luc Willems

Language(s) of instruction

French language

Organisation and examination

Teaching in the first semester, review in January

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

This course unit is primarily based on laboratory experiments. Using model systems (microorganisms, plant cells, and animal cells), students will explore a range of molecular, biophysical, and bioinformatic analysis techniques to clone a gene from a biological sample and characterize the corresponding protein (function, localization, and interaction with the cell membrane). The project will employ molecular biology techniques, imaging, bioinformatic analysis, and biophysical methods (fluorescence spectroscopy, isothermal titration calorimetry).  

Learning outcomes of the learning unit

This course covers the full range of molecular approaches currently employed by bioengineers for the study and cellular characterization of prokaryotes and eukaryotes, with a view to their utilization and valorization. These approaches encompass molecular, biochemical, biophysical, and bioinformatic aspects. Upon completion of this multidisciplinary module, students will be able to understand, master, implement, and design molecular strategies to address complex biological problems in the fields of agronomy and bioengineering. Furthermore, students will be capable of optimizing existing processes in applied chemistry, biophysics, and biology to meet specific requirements.

Prerequisite knowledge and skills

CHIM0715-1 Applied Genoproteomics
BIOL2015-3 Molecular biology

Planned learning activities and teaching methods

Learning concepts will be mainly in the form of practical works organized inside the platform of molecular biology and associated laboratories.

Mode of delivery (face to face, distance learning, hybrid learning)

Face-to-face course


Further information:

- The attendance at the exercice sessions and practicals is mandatory.

- The experimental data will be analyzed and interpreted to draft a report.

Course materials and recommended or required readings

Recent publications of the scientific literature, books.

Exam(s) in session

Any session

- In-person

oral exam

Written work / report


Further information:

- written report

- oral presentation of the report

Work placement(s)

Organisational remarks and main changes to the course

Practicals will be organized on-site in the molecular biology laboratory.

The research project will be presented orally.

Contacts

Professor Martine Schroyen and Luc Willems

Martine.Schroyen@uliege.be

luc.willems@uliege.be

 

Association of one or more MOOCs