Duration
Natural raw materials : 20h Pr
Analysis of biological drugs and drugs in biofluids : 10h Th
Drug design : 10h Th
Industrial pharmaceutical technology : 10h Th
Sterilisation methods : 10h Th
Number of credits
| Master in pharmacy, professional focus in conception and development of medicine - bioanalysis | 5 crédits |
Lecturer
Natural raw materials : Michel Frederich, Allison Ledoux
Analysis of biological drugs and drugs in biofluids : Marianne Fillet
Drug design : Pierre Francotte
Industrial pharmaceutical technology : Brigitte Evrard, Anna Lechanteur
Sterilisation methods : Aurore Napp, Isabelle Roland, Gaëtan Van Haren
Language(s) of instruction
French language
Organisation and examination
Teaching in the second semester
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
Natural raw materials
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Drug design
This course covers the different stages of the design and production of biopharmaceuticals, with a particular focus on monoclonal antibodies and novel siRNA-based therapies. It addresses screening techniques, molecular modeling, rational drug design, studies of target interactions, as well as the production of recombinant proteins and the purification of monoclonal antibodies.
Innovative approaches currently being investigated for the development of new medicines will also be discussed.
Learning outcomes of the learning unit
Natural raw materials
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Drug design
By the end of this course, students will be able to:
1. Explain the key steps involved in the design and production of biopharmaceuticals.
2. Describe the fundamental principles of monoclonal antibodies and siRNA-based therapies.
3. Apply concepts of screening, molecular modeling, and rational drug design to practical examples.
4. Understand the processes of recombinant protein production and monoclonal antibody purification.
5. Critically analyze innovative approaches currently being investigated in drug development.
Prerequisite knowledge and skills
Natural raw materials
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Drug design
This course builds on prior knowledge in organic chemistry, pharmaceutical chemistry, biochemistry, and general pharmacology.
Planned learning activities and teaching methods
Natural raw materials
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Drug design
Course requiring active student participation.
Mode of delivery (face to face, distance learning, hybrid learning)
Natural raw materials
Face-to-face course
Further information:
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Drug design
Face-to-face course
Course materials and recommended or required readings
Natural raw materials
Platform(s) used for course materials:
- eCampus
- MyULiège
Further information:
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Drug design
Platform(s) used for course materials:
- eCampus
Natural raw materials
Exam(s) in session
Any session
- In-person
written exam
Other : Practical exam and written questions
Drug design
Exam(s) in session
Any session
- In-person
written exam ( multiple-choice questionnaire, open-ended questions )
Work placement(s)
Drug design
Information on internship opportunities within the laboratory will be provided to interested students.
Organisational remarks and main changes to the course
Contacts
Natural raw materials
Michel FREDERICH et Allison LEDOUX
Drug design
Pierre.Francotte@uliege.be
Université de Liège | Fac. de Médecine
B36 niv.+5 | Lab. de Chimie Pharmaceutique (CIRM)
Quartier Hôpital | Av. Hippocrate 15 | B-4000 Liège, Belgium