Duration
30h Th, 56h Pr
Number of credits
| Bachelor in pharmacy | 6 crédits |
Lecturer
Language(s) of instruction
French language
Organisation and examination
Teaching in the first semester, review in January
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
To complete the required theoretical concepts with a view to instrumental analysis in the pharmaceutical field.
To give students the necessary knowledge to use the following methods and skills:
- Introduction to separative techniques (Separation by change of state, distillation, rectification; fundamental chromatographic parameters).
- Thin Layer Chromatography, Gas Chromatography, High-performance Liquid Chromatography and Supercritical Fluid Chromatography.
- Capillary electrophoresis (principal characteristics of CE, Principle of electrophoresis, theory, electrophoretic mobility, electro-osmotic flow, apparatus).
Seminars linked with the theoretical course of Pharmaceutical Analytical Chemistry are also organized. The objective of these ones is to analyze some scientific publications in the analytical field in order to teach students to highlight rapidly relevant and useful information. These seminars allow to study the general structure of scientific publications and to teach how to reference correctly these publications.
Learning outcomes of the learning unit
To build on the required theoretical concepts with a view to instrumental analysis, in particular complete student training in the use of separation methods. To deal with the different aspects connected to the sample handling and the validation of instrument analysis techniques (Analytical methodology).
To contribute to the general education of future pharmacists on a theoretical and practical level in order to enable them to adopt an analytical approach to work. Teaching is centered on fundamental problems and those encountered in the analysis of medicines (Life cycle of analytical methods). To encourage an analytical and critical approach to work.
To teach students how to analyze scientific publications in the analytical field and how to highlight rapidly the relevant and useful information.
Prerequisite knowledge and skills
Preparatory chemistry for the biomedical and pharmaceutical sciences.
Physical and mathematical bases of biomedical sciences.
Introduction to Pharmaceutical Analytical Chemistry.
Planned learning activities and teaching methods
Theoretical teaching and seminars are supplemented by practical work. These ones enable to familiarize the students with quantification methods and characterization approaches of pharmaceutical raw materials and synthetic intermediates. Moreover, instrumental practical work is also organized in order to better understand some technical aspects broached during the theoretical lessons. All notes are available on the platform eCampus. The student will also use this platform to submit their results obtained during the practical work. For the titrimetric determination, the student will have to submit only one numerical data at the end of the practical work on the platform. This increase of the difficulty level is applied in continuation with the introduction in practical work in Pharmaceutical Analytical Chemistry. Regarding the instrumental practical work, a report template will be available on Ecampus. The completed report will have to be submitted on the platform to be corrected. The mean note obtained for the manipulations represents 50% of the final note of the practical work. Two interrogations including exercises related with the practical work will be organized. Collective corrections will be organized for each of them in the amphitheater. The mean of both represents 25% of the final note of the practical work. Finally, a written examination on the Pharmaceutical Analytical Chemistry practicals is organized outside the regular exam session. The result of this examination accounts for 25% of the final grade for the practicals.
Mode of delivery (face to face, distance learning, hybrid learning)
Blended learning
Further information:
Classes take place during the first term (Q5). Time: see the schedule on CELCAT.
Practical work: Place: student laboratory, level +4, tower 4 Building. B36. Time: see in the fascicule of practical works and on CELCAT
Attendance at practical work is mandatory.
Course materials and recommended or required readings
Platform(s) used for course materials:
- eCampus
Further information:
All notes for the theoretical course, the seminars and the practical work are available on the platform eCampus.
General works (recommended readings):"Analyse Chimique. Méthodes et techniques instrumentales modernes" (10ème édition); Rouessac, Ed. Dunod, 2025. "Chimie analytique"; Skoog, West, Holler (édition française, 4ème édition) Ed. De Boeck Université, 2023. "Analytical Chemistry", Christian, Dasgupta, Schug (7th Edition) Ed. Wiley, 2013.
Exam(s) in session
Any session
- In-person
written exam AND oral exam
Further information:
Theoretical work: Written exam on the subject defined by the professor and scientific staff.
Oral resit (first session only) in case of an insufficient score at the written exam.
An oral exam (first session only) is organised for students with a mark equal to or higher than 8.00/20 and lower than 10.00/20 in the written exam. This make-up oral exam is subject to prior registration. Criteria for rejection for the make-up oral exam: serious failure in the written exam.
Practical work: The total points for manipulations represent 50% of the practical work mark. Two written tests on exercises related to the practical work and the seminars are given during the practical work. The average of these will represent 25% of the final mark for the practical work. A written examination on the subject of all the activities relating to the practical work, including the essential prerequisites (Q4), is organised outside the session. The mark obtained for this examination represents 25% of the final mark for the practical work. The practical work results are included in the final score and are also carried over to the second session.
Attendance at practical work and associated activities (seminar and explanation session in the lecture theatre) is compulsory.
Any absence must be notified by email on the same day at the latest and then justified with an official document legally recognized in its country of issue which must be sent to the assistant responsible for organising the practical work, Madam Kemik (kevser.kemik@uliege.be) and Madam De Bleye (cdebleye@uliege.be) within 24 hours of the session concerned. Participation in 80% of the activities is compulsory in order to be able to take part in the examination relating to the practical work.
Work placement(s)
Training possibilities. Student-teachers: possibilities are available for students interested in teaching pharmaceutical analytical chemistry. The tasks involve supervising the practical work. Research: outside the course and exam periods (on finishing the 2nd year of the Bachelor in Pharmaceutical Sciences), motivated students may take part in a course in the laboratory (student-researchers). At the end of the course, there is a possibility of doing a PhD in the laboratory.
Organisational remarks and main changes to the course
The assistants are available to answer to the questions of the students but they have to take a appointment by email.
Contacts
Philippe Hubert, Professeur ordinaire
Service de Chimie Analytique Pharmaceutique, Département de Pharmacie, CHU Bât. B36, Quartier Hôpital, avenue Hippocrate 15, 4000 Liège
Tel. : 04/366.43.16
e-mail: ph.hubert@uliege.be
Eric Ziemons, Chargé de cours
Service de Chimie Analytique Pharmaceutique, Département de Pharmacie, CHU Bât. B36, Quartier Hôpital,avenue Hippocrate 15, 4000 Liège 1
Tel. : 04/366.43.16
e-mail: eziemons@uliege.be
Charlotte De Bleye, 1ère Assistante
Service de Chimie Analytique Pharmaceutique, Département de Pharmacie, CHU Bât. B36, Quartier Hôpital,avenue Hippocrate 15, 4000 Liège 1
Tél : +32 4 366.43.16
e-mail : cdebleye@uliege.be
Kevser Kemik, Doctorante
Service de Chimie Analytique Pharmaceutique, Département de Pharmacie, CHU Bât. B36, Quartier Hôpital,avenue Hippocrate 15, 4000 Liège 1
e-mail : b.saker@uliege.be
Secrétariat
Murielle Bihain, Service de Chimie Analytique Pharmaceutique, Département de Pharmacie, CHU Bât. B36, Quartier Hôpital,avenue Hippocrate 15, 4000 Liège 1
Tél : 04/366.43.16
e-mail: mbihain@uliege.be