CHIM0218-1

Duration

20h Th, 5h SEM

Number of credits

	Master in chemistry, research focus	3 crédits
	Master in chemistry, teaching focus (Réinscription uniquement, pas de nouvelle inscription)	3 crédits
	Master in chemistry, professional focus	3 crédits
	Master of education, Section 4: Chemistry	3 crédits

Lecturer

Pierre Francotte

Language(s) of instruction

French language

Organisation and examination

Teaching in the first semester, review in January

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

This course introduces the fundamental principles of drug design. It explores how new chemical entities have been discovered and continue to be selected for development as therapeutic agents. Emphasis is placed on the relationship between the chemical structure of a drug and its biological activity. Topics include structural modifications of known active compounds, structure-activity relationships, the pharmacophore concept, prodrugs, bioisosterism, the importance of stereochemistry, and drug-receptor interactions.

Learning outcomes of the learning unit

The aim of this course is to present students with the conceptual approaches, both traditional and innovative, that have led and continue to lead to the discovery of new medicines. It also seeks to highlight the close relationship between the pharmacological or therapeutic activity of a drug molecule and its chemical structure. Finally, since most drugs currently available on the market originate from organic synthesis, the course illustrates one of the key ways in which organic chemistry can be valorized.

Prerequisite knowledge and skills

Basic knowledge of inorganic and organic chemistry.

Planned learning activities and teaching methods

There is no practical work associated to this course.

Mode of delivery (face to face, distance learning, hybrid learning)

Face-to-face course

Further information:

Classes are scheduled in consultation with the students, in blocks of 2 to 3 hours.

Course materials and recommended or required readings

Platform(s) used for course materials:
- eCampus

Further information:

The course materials will be made available online progressively.

Exam(s) in session

Any session

- In-person

written exam ( multiple-choice questionnaire, open-ended questions )

Further information:

The written exam consists of a series of short-answer open questions designed to assess the overall understanding of the material covered.

Work placement(s)

none

Organisational remarks and main changes to the course