Duration
50h Th
Number of credits
Master in chemistry, research focus | 5 crédits | |||
Master in chemistry, teaching focus | 5 crédits | |||
Master in chemistry, professional focus | 5 crédits |
Lecturer
Language(s) of instruction
English language
Organisation and examination
Teaching in the second semester
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
Radioactivity plays an important role in our modern daily life. Chemistry is pivotal in taming this phenomenon for practical use in e.g. nuclear medicine or electricity production. This course aims at introducing and teaching you these two very specific experimental sciences that are nuclear chemistry and radiochemistry.
Course outline:
I. Introduction - Radioactivity
II. Nuclear Reactions
III. Electricity production
- Nuclear Power Plant
- Nuclear Waste treatment
IV. Nuclear Medicine
- Design and structural features of a radiopharmaceutical
- Covalent radiolabelling: 11C, 18F, and iodine
- Chelation radiolabelling: 68Ga, 89Zr, 99mTc, 117Lu
- Radionuclide Selection Guide for the design of radiopharmaceutical
- Nomenclature
- Daily life of a radiochemist: practical example of a production centre
V. Notions of radioprotection
Learning outcomes of the learning unit
At the end of this course, you will know what is radioactivity and the different type of nuclear reactions. You will have a reasonnable knowledge of how a nuclear power plant works and of the nuclear waste topic. You will also have a better understanding of the whole radiopharmaceutical production pipeline and where chemistry play a part. You will know the general categories of radiolabelling reactions. You will have a better understanding of the challenges to tackle for the futur of Nuclear Medicine.
Prerequisite knowledge and skills
Master level chemistry.
Planned learning activities and teaching methods
Mode of delivery (face to face, distance learning, hybrid learning)
Face-to-face course
Additional information:
This course has 12 lectures delivered during the second semester
Course materials and recommended or required readings
Lecture presentations are accessible online on myULiege.
Reading material:
Nuclear and radiochemistry : fundamentals and applications, LIESER. Berlin : Wiley-VCH, 2001
Radiopharmaceutical Chemistry, J. S. Lewis, A. D. Windhorst, B. M. Zeglis, Springer Nature, 2019, ISBN 978-3319989488
Chimie des radiotraceurs et applications biologiques, M. Comet et M. Vidal. EDP Science, 1998, ISBN: 2-86883-460-4
Oral exam
Work placement(s)
Organisational remarks and main changes to the course
Contacts
Thibault Gendron
Bât. B30 Centre de Recherche du Cyclotron
Quartier Agora
allée du Six Août 8
4000 Liège 1