2023-2024 / MICR1717-1

General and clinical microbiology


40h Th, 12h Pr

Number of credits

 Bachelor in pharmacy6 crédits 


Marie-Pierre Hayette



Language(s) of instruction

French language

Organisation and examination

Teaching in the second semester


Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

General microbiology (Prof. MP Hayette)


  • Introduction 
  • Historical milestones 
  • The microbial world
  • Bacteria, procaryotic cells 
  • Beneficial aspects of microbes 
  • Concepts of microbial diseases 
  • Control of microbial diseases: prevention and therapeutic approach
  • Fungi 
  • Parasites
Clinical microbiology (Pr. MP.Hayette, C. Meex)

This course is designed to provide you with basic knowledge of medical microbiology. It follows the general microbiology course you received last year giving basic knowledge on microorganisms and host-parasite relationships. You approach this year the main infectious diseases encountered in the community. These will be addressed by anatomical site such as infections of the urogenital tract or respiratory tract because they are among the most commonly encountered.

This course will allow those who will work in an Pharmacy to best ensure their advisory role in prevention and treatment of infectious diseases. For who will choose the domain of clinical biology, the course will provide the foundation of the knowledge which will be reinforced during the master's degree. Finally for those who will choose for industry or research branches, the knowledge of general and clinical microbiology will provide a basis necessary to work in different fields such as for example the field of anti-infectives. 

Course contents

The course will focus on the epidemiology, clinical signs, diagnostic, therapy and prevention methods. The anti-infective molecules will be detailed in connection with the resistance developed by microorganisms and major side effects. 
Indeed, the course provides a link between anti-infectives and the target organism to better understand the interactions and the development of potential resistance.

NB. Viral infections will not be addressed (cf. course given by Prof. N. Jacobs).

Microorganisms and the diseases they induce will be addressed by anatomical site. Be addressed: respiratory tract infections especially pneumonia of bacterial origin including tuberculosis; urinary tract infections, as well as sexually transmitted diseases such as infections due to Chlamydia trachomatis, Neisseria gonorrhoeae and syphilis: infections transmitted by arthropods like Lyme disease and malaria (imported tropical disease). Mother-child infections: toxoplasmosis. Finally, the main mechanisms of resistance to antibiotics, will include: types of mechanisms, mode of acquisition, prevalence.

Learning outcomes of the learning unit

Partim General microbiology

At the end of the course, the student will be able to:

  • identify the main microbial challenges on the earth
  • describe the importance of mortality associated to infectious diseases and the evolution/emergence of infectious diseases
  • summarize a few important milestones in the microbial history
  • describe the different groups of microorganisms and their characteristics
  • explain the important role and characteristics of biofilms
  • describe the main points of bacterial genetics and genome plasticity
  • report the principles of beneficials aspects of microbes
  • summarize the different symbiotic and pathogenic  relationships between microorganisms and human beings.
  • list the main bacterial virulence factors
  • describe the different modes of transmission of microbes to or between human beings
  • understand and summarize human defenses against microbial attack and prevention strategies (food security, access to drinking water, vaccines, sterilization - disinfection, antibiotics).
  • list the main groups of antibiotics, mode of action and resistance mechanisms
  • describe the principles of the main microbial methods used for clinical diagnostics

Partim Clinical microbiology

At the end of the course you will have enriched your knowledge of the epidemiology of major infectious diseases encountered in the community, with focus on prevention and therapeutic. 

You will know the main techniques used in a microbiology laboratory for the diagnosis of infectious diseases.

Prerequisite knowledge and skills

The prerequisite knowledges are:

  • General biology
  • General Immunology.
The co-requesite knowledge is:

  • General and medical virology (Pr N. Jacobs).

Planned learning activities and teaching methods

General microbiology

The course is taught as lectures, supported by PowerPoint-type slides.

Students are invited to ask their questions after the lecture or by email.

Practical work sessions are compulsory.  They illustrate the theoretical course.  Biosecurity and hand hygiene are introduced at the first session


Clinical microbiology

The course will be presented in the form of lectures. Practical sessions are also organized. Tutorials are presented in the form of workshops that illustrate the lectures through demonstration of diagnostic tests, microscopical and macroscopical observations (bacterial and fungal cultures, observation of adult parasites).

Mode of delivery (face to face, distance learning, hybrid learning)

Face-to-face course

Additional information:

Face-to-face course

Participation of two lecturers

Prof. MP Hayette and Pharm biol C. Meex

Practical works sessions
coordinated by Rosalie SACHELI, ULiège

Attendance is compulsory

Slide sets and lab syllabus available online

Recommended or required readings

Slide sets of theoretical lectures  as well as syllabus of pratical works, posted on the ULg website, which can be downloaded by the concerned students, are compulsory.

The following books are good references related to the course:

  • MIMS' MEDICAL MICROBIOLOGY, Mims C. et al, 6th Ed.,2018, Elsevier
  • INTRODUCION A LA MICROBIOLOGIE, Tortora G.J. et al, 2nd Ed., 2012, ERPI, Editions du Renouveau Pédagogique Inc.
  • BROCK BIOLOGY OF MICROORGANISMS, MT Madigan et al, 14th Ed, 2014,Pearson
  • MICROBIOLOGIE, Prescott, Willey JM et al, Traduction de la 8ème Ed,2013, Ed.De Boeck Université
  • INFECTIOLOGIE, Tome 3. 3ème édition. Collection Le moniteur internat. 2007
Site web recommandé

Exam(s) in session

Any session

- In-person

written exam

Additional information:

Written examinations for the theorical (June / September) (multiple choice questions, open questions with short answers).

Written evaluation (multiple choice questions +/- open questions with short answers) for the practical works, organized after the last SEANCE of each group.  The evaluation is included for 10% in the notes obtained in the first session.

if the written exam is not possible due to the sanitary situation, online exam will be organized.

Work placement(s)

Opportunity for a 3-month internship during the last year of master and production of a final thesis

Organisational remarks and main changes to the course

For practical works session

  • the coordinator is Rosalie SACHELI, university hospital of Liege
  • Attendance is compulsory
  • Access is restricted only to students wearing a labcoat.


Clinical Microbiology department
University hospital of Liège,
B-23 Sart Tilman,
4000 LIEGE

For any contact or appointment request, please address your demand to the secretary Mrs S Wauquier

  • Phone:
  • Telecopy:
  • email: micromed@uliege.be

Professors and lecturers

Marie-Pierre Hayette: mphayette@uliege.be

C. Meex: C.Meex@chuliege.be


Rosalie SACHELI, R.Sacheli@chuliege.be


Association of one or more MOOCs