2023-2024 / CHIM0678-1



30h Th

Number of credits

 Bachelor in chemistry3 crédits 


André Matagne

Language(s) of instruction

French language

Organisation and examination

Teaching in the first semester, review in January


Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

Chapter I. Protein structure: I.1. Amino acids; I.2. Peptide bond; I.3. Non-covalent interactions; I.4. Secondary structure; I.5. Tertiary and quaternary structures; I.6. Fibrous and globular proteins; I.7. Protein folding. Chapter II. Protein function: II.1. Myoglobin and Hemoglobin, two oxygen carrier proteins; II.2. Enzymes. Chapter III. Biological membranes: III.1. Lipids; III.2. Lipid bilayers; III.3. Membrane proteins; III.4. Structure of membrane proteins. Chapter IV. Nucleic acid and the flow of genetic information: IV.1. Nucleotides; IV.2 Polarity of nucleic acids; IV.3. DNA structure; IV.4. DNA replication; IV.5. Gene expression. Chapter V. Metabolism: V.1. Glycolysis and gluconeogenesis; V.2. Krebs cycle; V.3 Oxidative phosphorylation; V.4. Photosynthesis.

Learning outcomes of the learning unit

The aim of these lectures is to teach students with fundamentals in biochemistry, i.e. 1) the structure of biological (macro)molecules, namely proteins, nucleic acids, lipids and carbohydrates; 2) their organization and function; 3) their metabolism. Emphasis will be given on the application of basic chemical principles in the life sciences.

Prerequisite knowledge and skills

Basic chemistry, biology and maths as taught for the first two years of the BAC.

Planned learning activities and teaching methods

30 hours of lectures, given with the help of powerpoint presentations, blackboard and white chalk.

Mode of delivery (face to face, distance learning, hybrid learning)

Face-to-face course

Additional information:

Face-to-face only

Recommended or required readings

Lecture notes will be available as the course progresses.
Reference book:
Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto, Jr., Lubert Stryer (2019) Biochemistry, 9th edition, W.H. Freeman and Co., New York.
David L. Nelson, Michael M. Cox (2017) Lehninger - Principles of Biochemistry, 7th edition, Macmillan Higher Education, Basingstoke, England.

Exam(s) in session

Any session

- In-person

written exam ( open-ended questions ) AND oral exam

Additional information:

A mixed oral and written exam will be organized. The oral part is for ca. 30-40 min, with maximum 15-20 min of preparation and thus minimum15-20 min of discussion. For the written part (30-40 min) the student will have to solve a problem, as discussed for the lectures.

Work placement(s)

Non applicable

Organisational remarks and main changes to the course

Lectures will be organized following the schedule known by the students. The professor will inform the students in advance of any possible modification to this.


André Matagne, PhD, Full Professor, Enzymology and Protein Folding, Centre for Protein Engineering, Life Science Department, Institut de Chimie B6c (room 3/1), Quartier Agora, Allée du 6 Août, 13, University of Liège, B4000 Liège (Sart-Tilman), Tel.: +32 (0)4 3663419, Fax: +32 (0)4 3663396, Email: amatagne@ulg.ac.be

Association of one or more MOOCs