Biology of the reproduction

Duration

20h Th

Number of credits

Lecturer

Michelle Nisolle

Language(s) of instruction

French language

Organisation and examination

Teaching in the first semester, review in January

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

Physiology in reproductive medicine

• Hypothalamo-pituitary axis function
• Ovarian cycle
• Menstrual cycle
• Fecondation and embryonic implantation
• Troubles of the ovulation
• Stimulation of the ovulation
• Preservation of the fertility
• Anomalies of the female and male genital systems
• Male reproduction system, anatomy and physiology
• Troubles of the male reproduction
• Technics of assisted medical procedures

Learning outcomes of the learning unit

• Describe the role of hypothalamus in ovulation induction
• Describe the hypothalamic neuro-endocrine system
• Describe the relations between the hypothalamus and the pituitary gland
• Understand the importance of the pulsatility of GnRH secretion
• Describe the pulsatility of the GnRH during the cycle
• Describe the clinical consequences of continuous administration of GnRH
• Schematize the hypothalamo-pituitary secretions in relation with the ovarian and menstrual cycles
• Knowledge of the external and internal regulation of the hypothalomo-pituitary axis
• Describe the steroidal feedback on the hypothalamo-pituitary axis
• Describe the role of the pituitary hormones on the ovulation induction
• Describe the follicular growth until the ovulation
• Describe the different phases of the ovarian cycle and variations
• Describe endocrine and exocrine functions of the ovary
• Knowledge of the inhibines role on the ovarian cycle
• Knowledge the follicular atresia and the importance
• Describe the bi-cellular theoric of the steroidal ovarian secretion
• Describe the different steps of the steroidal hormones synthesis
• Describe how to determine the ovarian reserve
• Describe the mecanisms responsible of the ovulation
• Precise the role of the corpus luteum
• Compare the peripheric effects of the progesterone and oestrogens
• Describe and compare the different phases of the menstrual cycle
• Explain the initiation of the menstruations
• Describe the embryo implantation and trophoblastic invasion
• Describe the relation between the ovarian cycle and the menstrual cycle
• Describe the implantation window and its importance
• Describe the different possibilities to evaluate the clinical impregnation on oestrogens and progesterone
• Explain the importance of the LH-RH test in amenorrhea
• Explain the different possibilities to explore the ovarian function
• Explain the irregular cycles at the puberty and peri-menopausis
• What are the hormonal analysis needed to diagnose the menopausis
• Explain the role of the progesterone test
• Explain the mecanism of the hormonal contraception
• Explain the hormones producted by the placenta and the role of the human chorionic gonadotrophin (hCG)
• Knowledge of the anatomy and histology of the placenta
• Describe the different methods of ovarian stimulation
• Knowledge of the recent data about the ovarian cryopreservation
• Describe the different anomalies of the female genital tract
• Describe the normal anatomy of the male genital tract and its anomalies
• Explain the different causes of the female infertility
• Explain the different causes of the male infertility
• Knowledge of the different technics of assisted medical procedures

Prerequisite knowledge and skills

• Anatomy of the hypothalamo-pituitary system and of the female genital tract
• Histology of the female genital tract
• Embryology of the female genital tract

Planned learning activities and teaching methods

Mode of delivery (face to face, distance learning, hybrid learning)

Ex-Cathedra courses: 10x2 hours

• Hypothalamo-pituitary axis function
• Ovarian cycle
• Menstrual cycle
• Fecondation and embryonic implantation
• Troubles of the ovulation
• Stimulation of the ovulation
• Preservation of the fertility
• Anomalies of the female and male genital systems
• Male reproduction system, anatomy and physiology
• Troubles of the male reproduction
• Technics of assisted medical procedures

Recommended or required readings

Powerpoint available

Any session :

- In-person

written exam

- Remote

written exam

- If evaluation in "hybrid"

preferred in-person


Additional information:

Written exam

Work placement(s)

Organisational remarks and main changes to the course

Contacts

Professor Michelle NISOLLE michelle.nisolle@chu.ulg.ac.be
Secretary: Christelle Leclercq christelle.leclercq@chrcitadelle.be

Association of one or more MOOCs

Items online