2022-2023 / CHIM0621-2

Production and application of radioelements

Duration

15h Th, 3d FW

Number of credits

 University certificate in radiopharmacy - long training3 crédits 
 University certificate in radiopharmacy - short training3 crédits 
 Master in physics (120 ECTS)2 crédits 

Lecturer

Thibault Gendron

Language(s) of instruction

French language

Organisation and examination

Teaching in the second semester

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

Modern nuclear medicine relies extensively on the use of radioactive molecules, both for diagnosis and therapy. The design and manufacture of these molecules is the result of innovative experimental research in which chemistry plays a major role. This course aims at teaching you the basic notions of this very specific chemistry called "radiochemistry".

Course outline:

  • Introduction - Radioactivity in Medicine
  • Basics of radioactivity and nuclear reactions
  • Production by cyclotron: 11C, 18F, 68Ga
  • Production by generator: 68Ga, 99mTc
  • Production in nuclear reactors

Learning outcomes of the learning unit

At the end of this course, you will have a better understanding of the whole radiopharmaceutical production pipeline. You will know the general methods to produce radionuclides. The main aim of this lecture is to give you the skills and knowledge to be able to discuss and understand physicists, cyclotron engineers and radiochemists in your future employment as a radiopharmacist or physicist.

Prerequisite knowledge and skills

Basic general knowledge in chemistry, at least A-level, preferably bechelor level.

Planned learning activities and teaching methods

A guided tour of the Centre de Recherche du Cyclotron (B30) will be given to visualize in real life the different production methods (subject to availability).

Mode of delivery (face to face, distance learning, hybrid learning)

Face-to-face course


Additional information:

This course has 15 hours delivered during the second semester

Recommended or required readings

Lecture presentations are accessible online on myULiege.

Reading material:

Medical Isotope Production Without Highly Enriched Uranium, National Research Council, 2009, ISBN 978-0-309-13039-4. Available free of charge at http://www.nap.edu/catalog.php?record_id=12569

Radiopharmaceutical Chemistry, J. S. Lewis, A. D. Windhorst, B. M. Zeglis, Springer Nature, 2019, ISBN 978-3319989488

Chimie des radiotraceurs et applications biologiques, M. Comet et M. Vidal. EDP Science, 1998, ISBN: 2-86883-460-4

Oral exam

Work placement(s)

Organizational remarks

Contacts

Thibault Gendron

Bât. B30 Centre de Recherche du Cyclotron
Quartier Agora
allée du Six Août 8
4000 Liège 1

Association of one or more MOOCs