2021-2022 / SANT4031-1

Specific clinical domain

Clinical examination - general semiology

Diagnostic measurements - supplementary investigations

Special Pharmacology

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

Biochemistry and normal and pathological human physiology, Digestive system

Biochemistry and normal and pathological human physiology, Nephro-urinary system

Biochemistry and normal and pathological human physiology, Cardiovascular system

Biochemistry and normal and pathological human physiology, Respiratory system

Biochimie et physiologie humaines normales et pathologiques, Système nerveux

Duration

Clinical examination - general semiology : 4h Th, 6h Pr.
Diagnostic measurements - supplementary investigations : 5h Th
Special Pharmacology : 20h Th
Biochemistry and normal and pathological human physiology, Endocrine system and metabolism : 15h Th
Biochemistry and normal and pathological human physiology, Digestive system : 15h Th
Biochemistry and normal and pathological human physiology, Nephro-urinary system : 10h Th
Biochemistry and normal and pathological human physiology, Cardiovascular system : 10h Th
Biochemistry and normal and pathological human physiology, Respiratory system : 10h Th
Biochimie et physiologie humaines normales et pathologiques, Système nerveux : 5h Th

Number of credits

 Master in nursing sciences10 crédits 

Lecturer

Clinical examination - general semiology : Bernard Lambermont
Diagnostic measurements - supplementary investigations : Edmond Brasseur
Special Pharmacology : Vincent Seutin
Biochemistry and normal and pathological human physiology, Endocrine system and metabolism : Philippe Kolh
Biochemistry and normal and pathological human physiology, Digestive system : Didier Cataldo
Biochemistry and normal and pathological human physiology, Nephro-urinary system : Didier Cataldo
Biochemistry and normal and pathological human physiology, Cardiovascular system : Philippe Kolh
Biochemistry and normal and pathological human physiology, Respiratory system : Didier Cataldo
Biochimie et physiologie humaines normales et pathologiques, Système nerveux : Pierre Maquet

Language(s) of instruction

French language

Organisation and examination

Teaching in the second semester

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

Special Pharmacology

see in french

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

The course deals with normal and pathological human biochemistry and physiology, partim endocrine system and metabolism. In particular, it encompasses the following chapters:
1. Introduction
2. Mechanisms of action of hormones
3. The hormones of energy metabolism      
Energy metabolism      
Insulin and diabetes      
Glucagon      
Adrenaline      
Glucocorticoids      
Thyroid hormones
4. Gastrointestinal hormones
5. Water, electrolytes and mineral elements
6. Growth
7. Reproduction
Chapters VIII (cytokines) and IX (mediators) are removed from this year's materia

Biochemistry and normal and pathological human physiology, Digestive system

The course aims at allowing students to be able to understand human biochemistry and physiology
The different systems will be part of the course:
I. Cardio-vascular system. 
1. Elements of cardio-vascular physiology 2. Cardiac pump 3. Vascular System 4. Cardio-vascular homeostasis : cardiac output and arterial pressure 5. Principles of cardio-vascular physiopathology 6. Arterial hypertension 7. Coronary insufficiency 8. Cardiac failure

II. Respiratory system
1. Introduction to respiratory system 
2. Ventilation
3. Diffusion 
4. Circulation
5. Blood gazes
6. Control of pH
7. Gaz exchanges
8. Respiratory mechanics
9. Control of ventilation
10. Unusual conditions (altitude...). 
 
III. Digestive system 
1. Introduction
2. Regulation processes
3. Energy and metabolism
4. Regulation of intakes
5. Mouth
6. Oesophagus
7. Stomach
8. Hormons of digestive tract
9. Pancreas
10. Intestine absorption 
11. Liver 
12. Colon 
 
IV. Nephro-urinary system 
1. Introduction
2. Glomerular filtration
3. Tubular function
4. Water and ions regulation
5. Kidney pathophysiology 
6. Urinary tract


V. Endocrine system and metabolism
 
The course concerns human biochemistry and physiology, partim endocrine system and metabolism. In particular, it encompasses the following chapters:
1. Introduction
2. Mechanisms of action of hormones
3. The hormones of the energetic metabolism
   Energetic metabolism
   Insulin and diabetes
   Glucagon
   Epinephrine
   Glucocorticoids
   Thyroid hormones
4. Gastro-intestinal hormones
5. Water, electrolytes, and mineral elements
6. Growth
7. Reproduction
8. Cytokines
9. Mediators
 
VI Nervous system
Système sensoriels somatiques : somesthésie, vision, audition, gustation, olfaction
Système moteur somatique : unité motrice, contrôle segmentaire des unités motrices, contrôle supra-segmentaire, apprentissage
Cognition, émotion, comportement
Eveil et conscience
Homéostasie

Biochemistry and normal and pathological human physiology, Nephro-urinary system

The course aims at allowing students to be able to understand human biochemistry and physiology
The different systems will be part of the course:
I. Cardio-vascular system. 
1. Elements of cardio-vascular physiology 2. Cardiac pump 3. Vascular System 4. Cardio-vascular homeostasis : cardiac output and arterial pressure 5. Principles of cardio-vascular physiopathology 6. Arterial hypertension 7. Coronary insufficiency 8. Cardiac failure

II. Respiratory system
1. Introduction to respiratory system 
2. Ventilation
3. Diffusion 
4. Circulation
5. Blood gazes
6. Control of pH
7. Gaz exchanges
8. Respiratory mechanics
9. Control of ventilation
10. Unusual conditions (altitude...). 
 
III. Digestive system 
1. Introduction
2. Regulation processes
3. Energy and metabolism
4. Regulation of intakes
5. Mouth
6. Oesophagus
7. Stomach
8. Hormons of digestive tract
9. Pancreas
10. Intestine absorption 
11. Liver 
12. Colon 
 
IV. Nephro-urinary system 
1. Introduction
2. Glomerular filtration
3. Tubular function
4. Water and ions regulation
5. Kidney pathophysiology 
6. Urinary tract


V. Endocrine system and metabolism
 
The course concerns human biochemistry and physiology, partim endocrine system and metabolism. In particular, it encompasses the following chapters:
1. Introduction
2. Mechanisms of action of hormones
3. The hormones of the energetic metabolism
   Energetic metabolism
   Insulin and diabetes
   Glucagon
   Epinephrine
   Glucocorticoids
   Thyroid hormones
4. Gastro-intestinal hormones
5. Water, electrolytes, and mineral elements
6. Growth
7. Reproduction
8. Cytokines
9. Mediators
 
VI Nervous system
Système sensoriels somatiques : somesthésie, vision, audition, gustation, olfaction
Système moteur somatique : unité motrice, contrôle segmentaire des unités motrices, contrôle supra-segmentaire, apprentissage
Cognition, émotion, comportement
Eveil et conscience
Homéostasie

Biochemistry and normal and pathological human physiology, Cardiovascular system

The subject of this module relates to  Normal and Pathological Human Biochemistry and Physiology, partim cardiovascular system, broken down in the following chapters:  
The heart pump (Chapters I to V):  
- Functional architecture (Chapter I)      
   - Heart chambers      
    - Valvular apparatus  
- The automaticity of the pump (Chapter II)
    - The action potential  
    - Neuro-vegetative modulation
- The cardiac cycle (Chapter III)
   - The driving unit
   - The pressure-volume loop  
- Ventricular performance (Chapter IV)
   - The concept of preload
   - The concept of afterload
   - The concept of contractility  
- Myocardial energetics (Chapter V)
The vascular system (Chapter VI):  
- The laws of blood flow (Chapter VI)
   - Bernoulli's law
   - Darcy's law
   - Hagen-Poiseuille's law
- Functional architecture (Chapter VI)
   - Vascular resistance
   - Arterial elasticity  
- The blood pressure wave (Chapter VI)  
- Vasomotricity (Chapter VI)    
   - Mechanical self-regulation
   - Metabolic self-regulation
   - The endothelial function  
Cardiovascular control (Chapter VII)
- The relationships of cardiac output
- Control of blood pressure
   - The barosensitive reflex
   - Hormonal regulation  
Elements of cardiovascular physiopathology (Chapters VIII and X)
- Pressure overload (Chapter VIII)
- Volume overload (Chapter VIII)
- Breach of contractility (Chapter VIII)
- The vicious circle of heart failure (Chapter X)
- Circulatory insufficiencies (Chapter X)
   - Syncopes
   - Shocks

Biochemistry and normal and pathological human physiology, Respiratory system

The course aims at allowing students to be able to understand human biochemistry and physiology
The different systems will be part of the course:
I. Cardio-vascular system. 
1. Elements of cardio-vascular physiology 2. Cardiac pump 3. Vascular System 4. Cardio-vascular homeostasis : cardiac output and arterial pressure 5. Principles of cardio-vascular physiopathology 6. Arterial hypertension 7. Coronary insufficiency 8. Cardiac failure
II. Respiratory system
1. Introduction to respiratory system 
2. Ventilation
3. Diffusion 
4. Circulation
5. Blood gazes
6. Control of pH
7. Gaz exchanges
8. Respiratory mechanics
9. Control of ventilation
10. Unusual conditions (altitude...). 
 
III. Digestive system 
1. Introduction
2. Regulation processes
3. Energy and metabolism
4. Regulation of intakes
5. Mouth
6. Oesophagus
7. Stomach
8. Hormons of digestive tract
9. Pancreas
10. Intestine absorption 
11. Liver 
12. Colon 
 
IV. Nephro-urinary system 
1. Introduction
2. Glomerular filtration
3. Tubular function
4. Water and ions regulation
5. Kidney pathophysiology 
6. Urinary tract


V. Endocrine system and metabolism
 
The course concerns human biochemistry and physiology, partim endocrine system and metabolism. In particular, it encompasses the following chapters:
1. Introduction
2. Mechanisms of action of hormones
3. The hormones of the energetic metabolism
   Energetic metabolism
   Insulin and diabetes
   Glucagon
   Epinephrine
   Glucocorticoids
   Thyroid hormones
4. Gastro-intestinal hormones
5. Water, electrolytes, and mineral elements
6. Growth
7. Reproduction
8. Cytokines
9. Mediators
 
VI Nervous system
Système sensoriels somatiques : somesthésie, vision, audition, gustation, olfaction
Système moteur somatique : unité motrice, contrôle segmentaire des unités motrices, contrôle supra-segmentaire, apprentissage
Cognition, émotion, comportement
Eveil et conscience
Homéostasie

 

Learning outcomes of the learning unit

Special Pharmacology

xxx

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

The objective of the course is to master the principles of biochemistry and physiology of the human endocrine system and of the metabolism of the human organism. Furthermore, the student will have understood the importance of feedbacks and interactions between the different parts of the regulatory systems.
More specifically, the learning objectives correspond to the table of contents of the course, described in detail in the "contents of the teaching unit" section.

Biochemistry and normal and pathological human physiology, Digestive system

The objective of the course is to master the principles of biochemistry and physiology of the human cardio-vascular system. Furthermore, the student will have understood the importance of feedbacks and interactions between the different parts of the regulatory systems.

Biochemistry and normal and pathological human physiology, Nephro-urinary system

The objective of the course is to master the principles of biochemistry and physiology of the human cardio-vascular system. Furthermore, the student will have understood the importance of feedbacks and interactions between the different parts of the regulatory systems.

Biochemistry and normal and pathological human physiology, Cardiovascular system

The objective of the course is to master the principles of biochemistry and physiology of the human cardio-vascular system. Furthermore, the student will have understood the importance of feedbacks and interactions between the different parts of the regulatory systems.
More specifically, the learning objectives correspond to the table of contents of the course, described in detail in the "contents of the teaching unit" section.

Biochemistry and normal and pathological human physiology, Respiratory system

The objective of the course is to master the principles of biochemistry and physiology of the human cardio-vascular system. Furthermore, the student will have understood the importance of feedbacks and interactions between the different parts of the regulatory systems.

Prerequisite knowledge and skills

Special Pharmacology

general pharmacology

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

General Biochemestry; General Physiology

Biochemistry and normal and pathological human physiology, Digestive system

General Biochemestry; General Physiology

Biochemistry and normal and pathological human physiology, Nephro-urinary system

General Biochemestry; General Physiology

Biochemistry and normal and pathological human physiology, Cardiovascular system

General Biochemestry; General Physiology

Biochemistry and normal and pathological human physiology, Respiratory system

General Biochemestry; General Physiology

Planned learning activities and teaching methods

Special Pharmacology

xxx

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

Lectures with active participation of students. All classes are podcast.

Biochemistry and normal and pathological human physiology, Digestive system

Lectures with active participation of students

Biochemistry and normal and pathological human physiology, Nephro-urinary system

Lectures with active participation of students

Biochemistry and normal and pathological human physiology, Cardiovascular system

Lectures with active participation of students. All classes are podcast.

Biochemistry and normal and pathological human physiology, Respiratory system

Lectures with active participation of students

Mode of delivery (face to face, distance learning, hybrid learning)

Special Pharmacology

see vade mecum

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

Face-to-face delivery

Biochemistry and normal and pathological human physiology, Digestive system

Face-to-face delivery or on-line lessons

Biochemistry and normal and pathological human physiology, Nephro-urinary system

Face-to-face delivery or on-line lessons

Biochemistry and normal and pathological human physiology, Cardiovascular system

Face-to-face delivery

Biochemistry and normal and pathological human physiology, Respiratory system

Face-to-face delivery or on-line lessons.

Recommended or required readings

Special Pharmacology

xxx

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

Course syllabus, available on MyULg/eCampus

Biochemistry and normal and pathological human physiology, Digestive system

Course syllabus, available on MyULg/eCampus
For neurophysiology here is a useful reference book:
Neurosciences, 5th edition. D. Purves, G.J. Augustine, D. Fitzpatrick, W.C. Hall, A.-S LaMantia, J.O. McNamara, L.E. White. de boeck Ed<br /><br /> Course syllabus, available on MyULg/eCampus
For neurophysiology here is a useful reference book:
Neurosciences, 5th edition. D. Purves, G.J. Augustine, D. Fitzpatrick, W.C. Hall, A.-S LaMantia, J.O. McNamara, L.E. White. de boeck Ed<br /><br /> Course syllabus, available on MyULg/eCampus
For neurophysiology here is a useful reference book:
Neurosciences, 5th edition. D. Purves, G.J. Augustine, D. Fitzpatrick, W.C. Hall, A.-S LaMantia, J.O. McNamara, L.E. White. de boeck Ed<br /><br /> Course syllabus, available on MyULg/eCampus
For neurophysiology here is a useful reference book:
Neurosciences, 5th edition. D. Purves, G.J. Augustine, D. Fitzpatrick, W.C. Hall, A.-S LaMantia, J.O. McNamara, L.E. White. de boeck Ed

Biochemistry and normal and pathological human physiology, Nephro-urinary system

Course syllabus, available on MyULg/eCampus
For neurophysiology here is a useful reference book:
Neurosciences, 5th edition. D. Purves, G.J. Augustine, D. Fitzpatrick, W.C. Hall, A.-S LaMantia, J.O. McNamara, L.E. White. de boeck Ed<br /><br /> Course syllabus, available on MyULg/eCampus
For neurophysiology here is a useful reference book:
Neurosciences, 5th edition. D. Purves, G.J. Augustine, D. Fitzpatrick, W.C. Hall, A.-S LaMantia, J.O. McNamara, L.E. White. de boeck Ed

Biochemistry and normal and pathological human physiology, Cardiovascular system

Course syllabus, available on MyULg/eCampus

Biochemistry and normal and pathological human physiology, Respiratory system

Course syllabus, available on MyULg/eCampus
For neurophysiology here is a useful reference book:
Neurosciences, 5th edition. D. Purves, G.J. Augustine, D. Fitzpatrick, W.C. Hall, A.-S LaMantia, J.O. McNamara, L.E. White. de boeck Ed

Assessment methods and criteria

Special Pharmacology

Any session :

- In-person

oral exam

- Remote

oral exam

- If evaluation in "hybrid"

preferred in-person


Additional information:

xxx

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

Exam(s) in session

Any session

- In-person

written exam ( multiple-choice questionnaire )


Additional information:

End semester evaluations



Written evaluations will take place in june and in august/september. Evaluations will be organized the same day for all parts of the course Normal and Pathological Human Biochemistry and Physiology (NPHBP). 

For the endocrine and metabolism module, the exam consists of Multiple Choice Questions (MCQ).    

Biochemistry and normal and pathological human physiology, Digestive system

End semester evaluations
Written evaluations will take place in june and in august/september. Evaluations will be organized the same day for all parts of this teaching unit.
The following type of question is possible :
- Questions with long answer
 - Questions with short answer
 - Multiple choice 
Examinations will be organized on-line or as presential activities. 

Biochemistry and normal and pathological human physiology, Nephro-urinary system

End semester evaluations
Written evaluations will take place in june and in august/september. Evaluations will be organized the same day for all parts of this teaching unit.
The following type of question is possible :
- Questions with long answer
 - Questions with short answer
 - Multiple choice 
Examinations will take place on-line or as presential activities. 

Biochemistry and normal and pathological human physiology, Cardiovascular system

Exam(s) in session

Any session

- In-person

written exam ( multiple-choice questionnaire )


Additional information:

End semester evaluations

Written evaluations will take place in june and in august/september. Evaluations will be organized the same day for all parts of the course Normal and Pathological Human Biochemistry and Physiology (NPHBP). 

For the cardio-vascular module, the exam consists of Multiple Choice Questions (MCQ).

Biochemistry and normal and pathological human physiology, Respiratory system

End semester evaluations
Written evaluations will take place in june and in august/september. Evaluations will be organized the same day for all parts of this teaching unit.
The following type of question is possible :
- Questions with long answer
 - Questions with short answer
 - Multiple choice 
Exams will be organized either on-line or as presential activities.

Work placement(s)

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

No training

Biochemistry and normal and pathological human physiology, Digestive system

No training

Biochemistry and normal and pathological human physiology, Nephro-urinary system

No training

Biochemistry and normal and pathological human physiology, Cardiovascular system

No training

Biochemistry and normal and pathological human physiology, Respiratory system

No training

Organizational remarks

Special Pharmacology

xxx

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

No remark

Biochemistry and normal and pathological human physiology, Digestive system

No remark

Biochemistry and normal and pathological human physiology, Nephro-urinary system

No remark

Biochemistry and normal and pathological human physiology, Cardiovascular system

No remark

Biochemistry and normal and pathological human physiology, Respiratory system

No remark

Contacts

Special Pharmacology

Teacher :
Vincent Seutin
Laboratoire de Pharmacologie et GIGA Neurosciences, CHU Tour 4 (B36)
Avenue Hippocrate 15, 4000 Liège

Secretary :
Madame N. Lacroix (même adresse), Nastasia.Lacroix@uliege.be   Tél : +32 4 366 25 24

Biochemistry and normal and pathological human physiology, Endocrine system and metabolism

Pr Philippe Kolh
Philippe.kolh@uliege.be
04/3665196
04/3668445 (secretary)
 

Biochemistry and normal and pathological human physiology, Digestive system

Prof Didier CATALDO
didier.cataldo@uliege.be
Tel : 04 366 2521 
Mme Jessica THYS (administrative assistent)
Jessica.thys@uliege.be
 
 Pr Philippe Kolh
Philippe.kolh@uliege.be
04/3665196
04/3668445 (secretary)
 
Prof Gaetan GARRAUX
Tél : 04 3665950
ggarraux@uliege.be
Prof Didier CATALDO
didier.cataldo@uliege.be
Tel : 04 366 2521 
Mme Jessica THYS (administrative assistent)
Jessica.thys@uliege.be
 
 

Biochemistry and normal and pathological human physiology, Nephro-urinary system

Prof Didier CATALDO
didier.cataldo@uliege.be
Tel : 04 366 2521 
Mme Jessica THYS (administrative assistent)
Jessica.thys@uliege.be
 
 Pr Philippe Kolh
Philippe.kolh@uliege.be
04/3665196
04/3668445 (secretary)
 
Prof Gaetan GARRAUX
Tél : 04 3665950
ggarraux@uliege.be
Prof Didier CATALDO
didier.cataldo@uliege.be
Tel : 04 366 2521 
Mme Jessica THYS (administrative assistent)
Jessica.thys@uliege.be
 

Biochemistry and normal and pathological human physiology, Cardiovascular system

Pr Philippe Kolh
Philippe.kolh@uliege.be
04/3665196
04/3668445 (secretary)
 

Biochemistry and normal and pathological human physiology, Respiratory system

Prof Didier CATALDO
didier.cataldo@uliege.be
Tel : 04 366 2521 
Mme Jessica THYS (administrative assistent)
Jessica.thys@uliege.be
 
 Pr Philippe Kolh
Philippe.kolh@uliege.be
04/3665196
04/3668445 (secretary)
 
Prof Gaetan GARRAUX
Tél : 04 3665950
ggarraux@uliege.be