2020-2021 / TOXI0002-1

Toxicological risk management in companies

Part 1 : General principles

Part 2 : Biological monitoring

Duration

Part 1 : General principles : 10h Th
Part 2 : Biological monitoring : 10h Th

Number of credits

 Specialised master in occupational medicine2 crédits  
 University certificate : training in professional pathology2 crédits  

Lecturer

Part 1 : General principles : Corinne Charlier
Part 2 : Biological monitoring : Corinne Charlier

Coordinator

Corinne Charlier

Language(s) of instruction

French language

Organisation and examination

Teaching in the second semester

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

Part 1 : General principles

The goal of this course is oriented to toxicological risk management in companies. Practical gestion of professional risk and use of available data bases will be discusssed.

Part 2 : Biological monitoring

This lecture "biological monitoring" is oriented to toxicological risk management in companies and to watching up the toxicological risk in vitro or by experimental techniques on animal, or on human (monitoring of contamination and its impacts).

Learning outcomes of the learning unit

Part 1 : General principles

To improve knowledge in

  • toxicological management in companies ;
  • professional risks management : primary prevention (identification of potent agents, quantitative evaluation of exposures, mastering of potent agents) and risk evaluation ;
  • data bases : practical advices to use on line data banks and software.

Part 2 : Biological monitoring

1. Experimental toxicology

1.1. Estimation of severity of toxicity by in vivo methods

1.1.1. Advantages and disadvantages of animal experimentation

1.1.2. Growing-up, maintenance and experimentation conditions

1.1.3. Test of acute toxicity

1.1.4. Test of intermediate toxicity

1.1.5. Test of chronic toxicity

1.2. Estimation of severity of toxicity by in vitro methods

1.3. Stochastic effects

2. Human toxicity

2.1. Contamination monitoring

2.2. Effects monitoring

Prerequisite knowledge and skills

Part 2 : Biological monitoring

Toxicological risk management in companies

Partim 1 : General principles, 10h Th

Planned learning activities and teaching methods

Part 1 : General principles

Not appliable

Mode of delivery (face to face, distance learning, hybrid learning)

Part 1 : General principles

10 hours (2nd semester)

Part 2 : Biological monitoring

Theorical lectures (2 or 3 times) of 2 or 3 hours, 2nd semester

Organisational adjustments related to the current health context

Part 1 : General principles

....

Recommended or required readings

Part 1 : General principles

Copy of slides

Part 2 : Biological monitoring

.Copy of slides

Assessment methods and criteria

Below you will find information on the evaluation methods planned for in-person and remote exams as well as those planned for hybrid sessions. Depending on how the health crisis evolves, the chosen method will be communicated to you no later than one month before the start of the exam session.

Part 1 : General principles

QCM or T/NT written exam in june (on site ou virtual according to health situation)

Part 2 : Biological monitoring

QCM or T/NT written exam in June (on site or virtual according to health situation)

Work placement(s)

Organizational remarks

Contacts

Part 1 : General principles

Clinical, Forensic and Environmental Toxicology laboratory
Bloc central +3 porte 166
CHU Sart-Tilman
Secrétariat:  04/3667683
C.Charlier@chuliege.be

Part 2 : Biological monitoring

Professeur Corinne CHARLIER
Clinical, Forensic and Environmental Toxicology laboratory
CHU B35
Sart-Tilman, B4000 Liège
Tél. 04/3667683
Fax 04/3668889
e-mail : C.Charlier@chuliege.be