Duration
15h Th, 5h Mon. WS
Number of credits
| Master in biomedicine (120 ECTS) | 2 crédits | |||
| Master in bio-informatics and modelling (120 ECTS) | 2 crédits | |||
| Master in biochemistry and molecular and cell biology (120 ECTS) | 2 crédits |
Lecturer
Language(s) of instruction
French language
Organisation and examination
Teaching in the second semester
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
Advanced methods in mass spectrometry.
Electrospray ionisation and fragmentation of biomolecules.
Native mass spectrometry - Analysis of macromolecular assemblies.
Hydrogen-deuterium exchanges coupled to mass spectrometry.
Chemical Cross-Linking monitored by mass spectrometry.
Basis of ion mobility.
Imaging by mass spectrometry: Principles and applications.
Learning outcomes of the learning unit
This course aims to present to the student the main mass spectrometry-based approaches useful in biology, biochemistry or again microbiology thematic.
The theory of each part will be illustrated by recent examples extracted from the literature.
Prerequisite knowledge and skills
Molecular structures, mainly peptides et proteins.
Notions of mass spectrometry.
Planned learning activities and teaching methods
Theory.
Exercises illustrating the course.
Visit of the laboratory and discovery of the main instruments.
Mode of delivery (face to face, distance learning, hybrid learning)
Presentiel, Laboratory and potential Seminar.
The students will have access of the course materials through the eCampus facility.
Organisational adjustments related to the current health context
During the most delicate periods of the health crisis, the course will be proposed online in the form of pre-recorded video capsules. Live question-and-answer sessions will be organized on request.
The exam is held in person, unless prohibited by the authorities. In this extreme case, the exam would then be organized online either via the eCampus platform or using other tools which will be communicated later.
Recommended or required readings
Assessment methods and criteria
Below you will find information on the evaluation methods planned for in-person and remote exams as well as those planned for hybrid sessions. Depending on how the health crisis evolves, the chosen method will be communicated to you no later than one month before the start of the exam session.
The exam will be divided into three parts:
1- True/False testing: to check the good understanding of the whole teaching.
2- Open questions: to allow a more global expression of the students on the dispensed learning.
3- Case study from the literature.
Work placement(s)
Organizational remarks
Contacts
Prof. Loïc Quinton Laboratory of Mass Spectrometry - MolSys Research Unit Bat B6C, Local 0/R66 Tel: +0032 4 366 3679 Email: loic.quinton@uliege.be