2020-2021 / BIOC0010-1

Human, normal and pathological biochemistry and physiology (COPIE)

Cardiovascular system

Respiratory system

Nervous system

Nervous system - specific concepts

Duration

Cardiovascular system : 10h Th
Respiratory system : 10h Th
Nervous system : 20h Th
Nervous system - specific concepts : 2h Pr.

Number of credits

Lecturer

Cardiovascular system : Philippe Kolh
Respiratory system : Didier Cataldo
Nervous system : Gaëtan Garraux
Nervous system - specific concepts : Gilles Vandewalle

Language(s) of instruction

French language

Organisation and examination

Teaching in the first semester, review in January

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

Cardiovascular system

The subject of this module relates to  Normal and Pathological Human Biochemistry and Physiology, partim cardiovascular system, broken down in the following chapters:  
The heart pump (Chapters I to V):  
- Functional architecture (Chapter I)      
   - Heart chambers      
    - Valvular apparatus  
- The automaticity of the pump (Chapter II)
    - The action potential  
    - Neuro-vegetative modulation
- The cardiac cycle (Chapter III)
   - The driving unit
   - The pressure-volume loop  
- Ventricular performance (Chapter IV)
   - The concept of preload
   - The concept of afterload
   - The concept of contractility  
- Myocardial energetics (Chapter V)
The vascular system (Chapter VI):  
- The laws of blood flow (Chapter VI)
   - Bernoulli's law
   - Darcy's law
   - Hagen-Poiseuille's law
- Functional architecture (Chapter VI)
   - Vascular resistance
   - Arterial elasticity  
- The blood pressure wave (Chapter VI)  
- Vasomotricity (Chapter VI)    
   - Mechanical self-regulation
   - Metabolic self-regulation
   - The endothelial function  
Cardiovascular control (Chapter VII)
- The relationships of cardiac output
- Control of blood pressure
   - The barosensitive reflex
   - Hormonal regulation  
Elements of cardiovascular physiopathology (Chapters VIII and X)
- Pressure overload (Chapter VIII)
- Volume overload (Chapter VIII)
- Breach of contractility (Chapter VIII)
- The vicious circle of heart failure (Chapter X)
- Circulatory insufficiencies (Chapter X)
   - Syncopes
   - Shocks

Learning outcomes of the learning unit

Cardiovascular system

The objective of the course is to master the principles of biochemistry and physiology of the human cardio-vascular system. Furthermore, the student will have understood the importance of feedbacks and interactions between the different parts of the regulatory systems.
More specifically, the learning objectives correspond to the table of contents of the course, described in detail in the "contents of the teaching unit" section.

Prerequisite knowledge and skills

Cardiovascular system

General Biochemestry; General Physiology

Planned learning activities and teaching methods

Cardiovascular system

Lectures with active participation of students. All classes are podcast.

Mode of delivery (face to face, distance learning, hybrid learning)

Cardiovascular system

Face-to-face delivery

Organisational adjustments related to the current health context

Cardiovascular system

Face-to-face course if code green or yellow; Distance learning in case of code orange or red case

Recommended or required readings

Cardiovascular system

Course syllabus, available on MyULg/eCampus

Assessment methods and criteria

Below you will find information on the evaluation methods planned for in-person and remote exams as well as those planned for hybrid sessions. Depending on how the health crisis evolves, the chosen method will be communicated to you no later than one month before the start of the exam session.

Cardiovascular system

Any session :

- In-person

written exam ( multiple-choice questionnaire )

- Remote

written exam ( multiple-choice questionnaire )

- If evaluation in "hybrid"

preferred in-person


Additional information:

End semester evaluations
Written evaluations will take place in june and in august/september. Evaluations will be organized the same day for all parts of the course Normal and Pathological Human Biochemistry and Physiology (NPHBP). 
For the cardio-vascular module, the exam consists of Multiple Choice Questions (MCQ).

Work placement(s)

Cardiovascular system

No training

Organizational remarks

Cardiovascular system

No remark

Contacts

Cardiovascular system

Pr Philippe Kolh
Philippe.kolh@uliege.be
04/3665196
04/3668445 (secretary)