2019-2020 / PHAR2222-1

Advances in Pharmacology and Toxicology II

Duration

35h Th, 15h AUTR

Number of credits

 Master in biomedicine (120 ECTS)5 crédits 

Lecturer

Corinne Charlier, Julien Hanson

Language(s) of instruction

English language

Organisation and examination

Teaching in the second semester

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

Use of in vivo and in vitro tests to evaluate toxicity of chemical substances and drugs

Learning outcomes of the learning unit

To evaluate toxicity of chemical substances and drugs, and before human use, several experimental steps must be done :

  • micro-organism tests : speed and cheap, but with a lot of disadvantages (cell wall, none micro-oranite, specificity of ADN repair mechansisms, etc...);
  • eukaryotic cells tests : allow to control exactly the concentration used but not the study of influence of metabolic activation/inactivation (important in the study of cancer);
  • in vivo tests : results more sensitive and easier to transpose to human; the choice of a species is the "key" choice ; it is determinated by taking into account metabolic process and detoxification mechanisms.

Prerequisite knowledge and skills

Having had success in "Toxicological precepts" of the former academic year

Planned learning activities and teaching methods

Not appliable

Mode of delivery (face-to-face ; distance-learning)

...

Recommended or required readings

...

Assessment methods and criteria

Oral evaluation in january

Work placement(s)

Organizational remarks

Contacts

Professeur Corinne CHARLIER

Clinical,Forensic and Environmental Toxicological laboratory

CHU B35

Sart-Tilman, B4000 Liège

Tél.04/3667683

Fax 04/3668889

e-mail : C.Charlier@chu.ulg.ac.be

Adaptation of teaching commitments following the COVID-19 pandemic for the May-June 2020 session

Teaching methods implemented : distance-learning

In the class for partim 1 and in video for partim 2

Assessment subjects

Toxicology part (Corinne Charlier): All
Pharmacology part (Julien Hanson): All the content except drugs used in obesity, hormonal system, antiinfectious, anticancer and immunomodulators. 

Assessment methods

Toxicology part (Corinne Charlier): QCM on line
Pharmacology part (Julien Hanson): on line exam (open questions)

Contacts

See above

Adaptation of teaching commitments following the COVID-19 pandemic for the Aug-Sept 2020 session

Assessment subjects

Toxico Charlier : same  than in June
Pharmaco Hanson: same than in June

Assessment methods

Toxico Charlier : QCM on e-campus
Pharmaco Hanson: Open questions with short answers on e-campus 

Contacts

See above