Duration
15h Th, 5h Mon. WS
Number of credits
Lecturer
Language(s) of instruction
French language
Organisation and examination
Teaching in the second semester
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
Advanced methods in mass spectrometry.
Electrospray ionisation and fragmentation of biomolecules.
Native mass spectrometry - Analysis of macromolecular assemblies.
Hydrogen-deuterium exchanges coupled to mass spectrometry.
Chemical Cross-Linking monitored by mass spectrometry.
Basis of ion mobility.
Imaging by mass spectrometry: Principles and applications.
Learning outcomes of the learning unit
This course aims to present to the student the main mass spectrometry-based approaches useful in biology, biochemistry or again microbiology thematic.
The theory of each part will be illustrated by recent examples extracted from the literature.
Prerequisite knowledge and skills
Molecular structures, mainly peptides et proteins.
Notions of mass spectrometry.
Planned learning activities and teaching methods
Theory.
Exercises illustrating the course.
Visit of the laboratory and discovery of the main instruments.
Mode of delivery (face-to-face ; distance-learning)
Presentiel, Laboratory and potential Seminar.
The students will have access of the course materials through the eCampus facility.
Recommended or required readings
Assessment methods and criteria
The exam will be divided into three parts:
1- True/False testing: to check the good understanding of the whole teaching.
2- Open questions: to allow a more global expression of the students on the dispensed learning.
3- Case study from the literature.
Work placement(s)
Organizational remarks
Contacts
Prof. Loïc Quinton Laboratory of Mass Spectrometry - MolSys Research Unit Bat B6C, Local 0/R66 Tel: +0032 4 366 3679 Email: loic.quinton@uliege.be
Adaptation of teaching commitments following the COVID-19 pandemic for the May-June 2020 session
Teaching methods implemented : distance-learning
The missing courses will be proposed as podcasts. The students will have acces to the slides, and the professor will be available by email for answering to any question they may have.
Assessment subjects
The evaluation will concern all the subject taught face to face or by podcasting.
Assessment methods
The exam will be proposed on-line through the eCampus facility. It will be made of multiple choice as well as open questions. The exam will not exceed 2h.
Contacts
Prof. Loïc Quinton
loic.quinton@uliege.be - Tel +0032 4 366 3679
Laboratory of Mass Spectrometry - Deputy Director
Biological Chemistry - Team Leader
MolSys Research Unit
Allée du six Aout 11 - Quartier Agora - Liège Université
B4000 -Liège 1 - Belgium
Adaptation of teaching commitments following the COVID-19 pandemic for the Aug-Sept 2020 session
Assessment subjects
Identical to the one of the first exam period, June 2020.
Assessment methods
The exam will be proposed on-line through the eCampus facility. It will be made of multiple choice as well as open questions. The exam will not exceed 2h.
Contacts
Prof. Loïc Quinton
loic.quinton@uliege.be - Tel +0032 4 366 3679
Laboratory of Mass Spectrometry - Deputy Director
Biological Chemistry - Team Leader
MolSys Research Unit
Allée du six Aout 11 - Quartier Agora - Liège Université
B4000 -Liège 1 - Belgium