Duration
25h Th, 25h Pr
Number of credits
| Master in bio-informatics and modelling (120 ECTS) | 4 crédits |
Lecturer
Coordinator
Language(s) of instruction
French language
Organisation and examination
Teaching in the first semester, review in January
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
Objectives and program:
1) the tools needed for visualization and analysis of biological macromolecules,
2) an overview of protein modeling methods: homology modeling, ab initio modeling, proteins and ligands, docking methods, etc ...
The course will cover
- a reminder of the protein structure (if necessary ...),
- an introduction to the Protein Data Bank and description of a PDB file,
- an introduction to the Pymol visualization program and TPs on its use,
- the use of 3D structural analysis software (deepview software, PDBePISA)
- modeling by homology - Introduction to the Yasara and TP program on its use
- Protein-Ligand interactions - Introduction to AUTODOCK software
Learning outcomes of the learning unit
Prerequisite knowledge and skills
Planned learning activities and teaching methods
The use of the different software discussed requires the use of a laptop.
Mode of delivery (face-to-face ; distance-learning)
Face to face
Recommended or required readings
Power points Softwares access
Assessment methods and criteria
The exam will be oral and will consist of 2 parts:
- interrogation on the theory
- Presentation, in the form of a seminar (powerpoint), of a practical case whose title will be given in advance.
Work placement(s)
Organizational remarks
25 lessons of 2 hours, at the rate of 2 lessons / week of weeks S1 to S13.
Contacts
Paulette Charlier, PhD, Chargé de Cours
Cristallographie des macromolécules biologiques, Centre d'Ingénierie des Protéines, Département des Sciences de la Vie, Université de Liège, Institut de Physique, B5a, B-4000 Liège, Belgium
Tel: +32 (0)4 366 36 19
Fax: +32 (0)4 366 49 54
E-mail : paulette.charlier@uliege.be
http://www.cip.ulg.ac.be
Frédéric Kerff- Tél. 04/366.36.20 - E-mail : fkerff@uliege.be