Duration
20h Th, 10h Mon. WS
Number of credits
Lecturer
Language(s) of instruction
French language
Organisation and examination
Teaching in the second semester
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
This series of lectures is based on the use of biophysical methods (mainly optical spectroscopies, presented into details for course BIOC0721-1: Propriétés optiques des macromolécules biologiques) to study protein folding. Concrete examples (e.g. bêta-lactamases, single-domain antibody fragments, lysozymes) are analyzed in details, on the basis of theoretical background and data found in the literature. The course starts with an introduction to protein folding (in English)
Learning outcomes of the learning unit
Students will learn how some biophysical methods can be used to study protein folding.
Prerequisite knowledge and skills
General knowledge about proteins and spectroscopic methods
Planned learning activities and teaching methods
Lectures are given with the help of powerpoint presentations, blackboard and white chalk
Mode of delivery (face-to-face ; distance-learning)
Face-to-face only
Recommended or required readings
Scientific articles will be given as they are analyzed and lecture notes will be available following the lectures
Assessment methods and criteria
An oral will be organized. Each student is given ca. 30 min, with maximum 15 min for preparation and thus minimum 15 min for discussion.
Work placement(s)
Non applicable
Organizational remarks
Lectures will be organized following the schedule known by the students. The professor will inform the students in advance of any possible modification to this
Contacts
André Matagne, PhD, Full Professor, Enzymology and Protein Folding, Centre for Protein Engineering, Life Science Department, Institut de Chimie B6c (room 3/1), Quartier Agora, Allée du 6 Août, 13, University of Liège, B4000 Liège (Sart-Tilman), Tel.: +32 (0)4 3663419, Fax: +32 (0)4 3663396, Email: amatagne@ulg.ac.be
Adaptation of teaching commitments following the COVID-19 pandemic for the May-June 2020 session
Teaching methods implemented : distance-learning
Assessment subjects
Assessment methods
Students have received papers and the procedure to choose and analyse those they have chosen for their report.