Duration
10h Th
Number of credits
| Master in biomedicine (120 ECTS) | 2 crédits |
Lecturer
Language(s) of instruction
French language
Organisation and examination
Teaching in the first semester, review in January
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
Use of in vivo and in vitro tests to evaluate toxicity of chemical substances and drugs
Learning outcomes of the learning unit
To evaluate toxicity of chemical substances and drugs, and before human use, several experimental steps must be done :
- micro-organism tests : speed and cheap, but with a lot of disadvantages (cell wall, none micro-oranite, specificity of ADN repair mechansisms, etc...);
- eukaryotic cells tests : allow to control exactly the concentration used but not the study of influence of metabolic activation/inactivation (important in the study of cancer);
- in vivo tests : results more sensitive and easier to transpose to human; the choice of a species is the "key" choice ; it is determinated by taking into account metabolic process and detoxification mechanisms.
Prerequisite knowledge and skills
Having had success in "Toxicological precepts" of the former academic year
Planned learning activities and teaching methods
Not appliable
Mode of delivery (face-to-face ; distance-learning)
...
Recommended or required readings
...
Assessment methods and criteria
Oral evaluation in january
Work placement(s)
Organizational remarks
Contacts
Professeur Corinne CHARLIER
Clinical,Forensic and Environmental Toxicological laboratory
CHU B35
Sart-Tilman, B4000 Liège
Tél.04/3667683
Fax 04/3668889
e-mail : C.Charlier@chu.ulg.ac.be