MICR1717-1

Duration

40h Th, 12h Pr

Number of credits

	Bachelor in pharmacy	6 crédits

Lecturer

Marie-Pierre Hayette, Pierrette Melin

Coordinator

N...

Language(s) of instruction

French language

Organisation and examination

Teaching in the second semester

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

General microbiology (P.Melin and MP Hayette)
Contents:

Introduction (P. Melin)
Historical milestones (P. Melin)
The microbial world (P. Melin)
Bacteria, procaryotic cells (P. Melin)
Beneficial aspects of microbes (P. Melin)
Concepts of microbial diseases (P. Melin)
Control of microbial diseases: prevention and therapeutic approach (P. Melin)
Fungi (MP. Hayette)
Parasites (MP. Hayette)

Clinical microbiology (MP.Hayette)
This course is designed to provide you with basic knowledge of medical microbiology. It follows the general microbiology course you received last year giving basic knowledge on microorganisms and host-parasite relationships. You approach this year the main infectious diseases encountered in community. These will be addressed by anatomical site such as infections of the urogenital tract or respiratory tract because they are among the most commonly encountered.
This course will allow those who are destined to the pharmacy to best ensure their advisory role in prevention and treatment. For one who is destined to clinical biology, the course will provide the foundation reinforced during his training as a biologist. Finally for those who are destined for the industry or research, knowledge of medical microbiology provide a basis for the one who works in the sector of anti-infectives. For others, it will be a general microbiological knowledge.
Course Description
The course will focus on the epidemiology, clinical signs, diagnostic and therapeutic aspects. The anti-infective molecules will be detailed in connection with the resistance developed by microorganisms and major side effects.
Indeed, the course provides a link between anti-infectives and the target organism to better understand the interactions and the development of potential resistance.
NB. Infectious diseses will be addressed with the exception of viral infections that will be covered in the course of medical virology (Prof. N. Jacobs).

Contents
Diseases will be addressed by anatomical site. Be addressed: respiratory tract infections especially pneumonia of bacterial origin including tuberculosis; Urinary tract infections, as well as sexually transmitted diseases such as infections due to Chlamydia trachomatis, Neisseria gonorrhoeae and syphilis: Skin infections with emphasis on infections caused by S. aureus, superficial fungal infection (Candida, dermatophytes) and ectoparasites (lice, fleas); infections transmitted by arthropods like Lyme disease and malaria (imported tropical disease). Finally, the main mechanisms of resistance to antibiotics, antifungal and antiparasitic will include: types of mechanisms, mode of acquisition, prevalence.

Revision-Training
Continuously at the beginning of each course you will be interviewed by a quiz on the material covered previously. This will allow you to maintain your knowledge.
A review session is scheduled at the end of the course.

Learning outcomes of the learning unit

Partim General microbiology
At the end of the course, the student will be able to:

identify the main microbial challenges on the earth
describe the importance of mortality associated to infectious diseases and the evolution/emergence of infectious diseases
summarize a few important milestones in the microbial history
describe the different groups of microorganisms and their characteristics
explain the important role and characteristics of biofilms
describe the main points of bacterial genetics and genome plasticity
report the principles of beneficials aspects of microbes
summarize the different symbiotic and pathogenic relationships between microorganisms and human beings.
list the main bacterial virulence factors
describe the different modes of transmission of microbes to or between human beings
understand and summarize human defenses against microbial attack and prevention strategies (food security, access to drinking water, vaccines, sterilization - disinfection, antibiotics).
list the main groups of antibiotics, mode of action and resistance mechanisms
describe the principles of the main microbial methods used for clinical diagnostics

Partim clinical microbiology
At the end of the course you will have enriched your knowledge of the epidemiology of major infectious diseases encountered in the community, with focus on prevention and therapeutic.
You will know the main techniques used in a microbiology laboratory for the diagnosis of infectious diseases.

Prerequisite knowledge and skills

The prerequisite knowledges are

General biology
General Immunology.

The co-requesite knowledge is

General and medical virology (Pr N. Jacobs).

Planned learning activities and teaching methods

General microbiology
The course is taught as lectures, supported by PowerPoint-type slides.
Students are invited to ask their questions after the lecture or by email.
Practical work sessions are compulsory. They illustrate the theoretical course. Biosecurity and hand hygiene are introduced at the first session

Clinical microbiology
The course will be presented in the form of lectures. Practical sessions are also organized. Tutorials are presented in the form of workshops that illustrate the lectures through demonstration of diagnostic tests, microscopical and macroscopical observations (bacterial and fungal cultures, observation of adult parasites), projection of videos. On the other hand, a video will be made available as a virtual tour of the medical microbiology laboratory.

Mode of delivery (face-to-face ; distance-learning)

Face-to-face
Participation of two lecturers

P. Melin and MP Hayette for general microbiology
MP Hayette for clinical microbiology

Practical works sessions

coordinated by Julie Descy, pharmacist, specialist in clinical biology and microbiology, university hospital of Liege
attendance is compulsory

Slide sets and lab syllabus available online

Assessment methods and criteria

Written examinations for the theorical (June / September) (multiple choice questions, open questions with short answers). Written evaluation (multiple choice questions +/- open questions with short answers) for the practical works, organized after the last SEANCE of each group. The evaluation is included for 10% in the notes obtained in the first session.

Work placement(s)

Opportunity for a 3-month internship during the last year of master and production of a final thesis

Organizational remarks

For practical works session

the coordinator is Julie Descy, pharmacist, specialist in clinical biology and microbiology, university hospital of Liege
Attendance is compulsory
Access is restricted only to students wearing a labcoat.

Contacts

Clinical Microbiology department University hospital of Liège, B-23 Sart Tilman, 4000 LIEGE Belgium
Secretary For any contact or appointment request, please address your demand to the secretary Mrs MC Lhôte

Phone: 00.32.4.366.24.39
Telecopy: 00.32.4.366.24.40
email: micromed@uliege.be

Professors and lecturers
Pierrette Melin

Pierrette.Melin@uliege.be

Marie-Pierre Hayette

mphayette@uliege.be

Training
Julie Descy

julie.descy@chuliege.be

Items online

Appropriate antibiotic use
Powerpoint

Syllabus TP
The syllabus of the practical work resumes the methodologies used for the study of bacteria, yeasts, viruses. he described the serological reactions and the principles of molecular biology applied to microbiological diagnosis.

General and clinical microbiology