2018-2019 / METO0822-1

Introduction to translational research

Duration

30h Th

Number of credits

 Master in biomedicine (120 ECTS)3 crédits 
 Master in biomedicine (60 ECTS)3 crédits 

Lecturer

Stéphane Berghmans, François Jouret 

Language(s) of instruction

French language

Organisation and examination

Teaching in the second semester

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

The "Introduction to Translational Research" is a 30-hour course spread over 15 x 2 hours. Two professors share the teaching: Dr Stéphane Berghmans, VP Academic & Research Relations EU at Elsevier, and Dr François Jouret, nephrologist at Liège's CHU and postdoctoral specialist clinician at the FNRS.

Learning outcomes of the learning unit

The objectives of this 30-hour course entitled "Introduction to Translational Research" are:


  • to present translational research tools, situated at the border between basic sciences and clinical sciences; and the world of research;
  • to introduce the broader horizon to which translational research and research in general belong;
  • to explain the main experimental models of human diseases;
  • to rationalise the choice of an animal model depending on the question asked and/or disease studied;
  • to demonstrate the interest of translational research in understanding, diagnosing and treating human diseases;
  • to remind students of the experimental and ethical limitations of translational research;
  • to explain the difficulties of transposing some observations made in vitro and/or in vivo to man, and to identify the reasons why;
  • place translational research in its legal and regulating frameworks;
  • examine the science policy and the financing of translational research;
  • the influence of lobbying, networking and management on translational research.
  • to envisage the future of translational research, especially the position of bioinformatics.

Prerequisite knowledge and skills

Recommended optional programme components :
BIOL 2025-1 EPID 0430-1 NUTR 0718-1 QUAL 0438-1 SBIM 0451-1 SBIM 0451-2 SBIM 0477-1 SBIM 0481-2 SBIM 0492-1 TOXI 0441-1

Planned learning activities and teaching methods

The course will be taught as lectures, supported by PowerPoint-type slides.

Mode of delivery (face-to-face ; distance-learning)

Face-to-face

Recommended or required readings

Medical Physiology, 2e Updated Edition, by Walter F. Boron, Emile L. Boulpaep - Elsevier Ed.
The Immortal Life of Henrietta Lacks Paperback by Rebecca Skloot - Crown Books Ed. The American Journal of Translational Research, http://ajtr.org/
Improving your Research Management, by Alan M. Johnson - Elsevier Ed.
At the Helm, by Kathy Barker - CSHL Press

Assessment methods and criteria

Written exam in the 1st session Written exam in the 2nd session At the end of this course, students will be able to:


  • define the term "translational research" and describe the stages;
  • understand the different applications of translational research;
  • present a typical example of translational research in the fields of physiopathology, diagnosis and the treatment of human diseases;
  • critically examine the limitations of translational research;
  • understand the ethical stakes of translational research, both for animal models and the application to man of discoveries made in the laboratory;
  • envisage the future challenges of translational research.

Work placement(s)

./.

Organizational remarks

Classes will be taught in English.

Contacts

Dr François Jouret : Francois.jouret@chu.ulg.ac.be 04/366.25.40
Dr Stéphane Berghmans, s.berghmans@elsevier.com +32 471.78.19.00