2018-2019 / CHIM0716-1

From gene to protein

Duration

12h Th, 24h Pr, 12h AUTR

Number of credits

 Master in bioengineering : chemistry and bio-industries (120 ECTS)6 crédits 

Lecturer

Patrick Fickers, Laurence Lins, Sébastien Massart, Micheline Vandenbol, Hervé Vanderschuren, Luc Willems

Coordinator

Luc Willems

Language(s) of instruction

French language

Organisation and examination

Teaching in the first semester, review in January

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

The course includes laboratory practicals and writing of a research project.
 
1) Practicals about nucleic acids and proteins technologies will be performed in the laboratory.
Using model systems (microorganisms, vegetal and animal cells, the student will discover an overview of the molecular and bioinformatic techniques allowing cloning of a gene from a biological sample and characterization of the corresponding protein.

2) To describe a current scientific problem, concerning agronomic sciences and biological engineering, to which the students will have to answer by writing a research project of 4 pages in English.
The project will have to implement molecular techniques (technology of the nucleic acids, proteins and/or computer sciences in biology).
Each student will choose, according to his natural affinities, a research theme among those proposed by the teachers.

Learning outcomes of the learning unit

To approach all the molecular techniques currently developed by a bioingenior in the cellular characterization of the procaryotes and the eucaryotes for their exploitation and valorization. These approaches introduce genetics and genomics, biochemistry, bioinformatics and proteomics, and also immunology.
It is an option module following the Module of Master degree I CHIB, Applied genoproteomics.
At the end of this multidisciplinary module, the students must be able to understand and to implement solutions in complex biological problems using molecular approaches in the field of agronomic sciences and biological engineering.
At the end of the learning, the students must be able to optimize existing process in the field of chemistry and applied biology in order to answer to a specific context (certification EC).

Prerequisite knowledge and skills

CHIM0715-1 Applied Genoproteomics
BIOL2015-3 Molecular biology

Planned learning activities and teaching methods

Learning concepts will be mainly in the form of practical works organized for 8 days on the platform of molecular biology and associated laboratories.

Mode of delivery (face-to-face ; distance-learning)

- Practical works during 8 days are obligatory.
- Regular meetings with the concerned teachers will be organized in order to discuss about the progress of the research project.

Recommended or required readings

Recent publications of the scientific literature, books.

Assessment methods and criteria

The evaluation of knowledge will be based on the writing of a research project (in English) and also on an oral presentation.

Work placement(s)

Organizational remarks

Contacts

Professor Luc Willems
Molecular Biology
081/622157 luc.willems@uliege.be
 
Professor Micheline Vandenbol
Microbiology and Genomics
081/622353 m.vandenbol@uliege.be