CHIM0320-3

Duration

30h Th

Number of credits

	Bachelor in pharmacy	4 crédits

Lecturer

Philippe Hubert

Language(s) of instruction

French language

Organisation and examination

Teaching in the second semester

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

Analytical chemistry deals with the separation of matrix components, their identification and their quantitative determination. Quantitative analysis and measurements (or results) play a vital role in a number of industrial and research areas, include pharmacy and other sciences. Many analysts spend a considerable about of their time collecting quantitative information from often very complex matrices. Consequently, analytical chemistry is a very important tool for investigative research in a number of areas (chemical, biomedical, pharmaceutical...). Analytical chemistry therefore forms a core teaching unit in the Bachelor level in Pharmaceutical Sciences. It is based on the life cycle of analytical procedures, i.e. the resolution of problems covering the entire analytical life of the sample, from its origin to the final customer.
Clearly, all concepts intervening in the life cycle of an analytical procedure cannot be addressed in this introduction to analytical chemistry. The general analytical training of future pharmacists both in theoretical and practical terms, which be thus accomplished in the practical work in term Q4 (CHIM0231-1) and the course in term Q5.
To give to the students the theoretical basis necessary for the analysis of active ingredients used in pharmaceutical field. - Analytical Procedure (Life Cycle); - Presentation of results; - Types of error; - Expression of concentration levels (reminder).
To provide relevant information on the following techniques: - Titrimetry (acid-base titration, complexometric titration, redox titration, etc.). - Electroanalysis (Potentiometry, Electrolysis, Amperometry, Coulometry). - Atomic absorption and flame emission spectroscopy. - Molecular spectroscopy : Ultraviolet and visible absorption spectroscopy, Molecular fluorescence spectroscopy. - Vibrational Spectroscopy: Mid-infrared spectroscopy , Near-infrared spectroscopy and Raman. - Vibrational imaging.

Learning outcomes of the learning unit

To introduce the theoretical concepts necessary for the analysis of pharmaceutical active ingredients such as the expression of concentrations, the presentation of results and the types of errors.
To address the various technical aspects of spectroscopic methods.
To enable the future pharmacists to adopt an analytical approach to work.

Prerequisite knowledge and skills

General Chemistry (courses for biomedical and pharmaceutical students).
Physical and mathematical bases of biomedical sciences.

Planned learning activities and teaching methods

Practical exercises will take place independently of theoretical teaching (Practical exercises - Introduction to Analytical Chemistry, 100h - CHIM0321-1).

Mode of delivery (face-to-face ; distance-learning)

Presential.
Lectures are ex-cathedra.
Lectures during Q4. Schedule: see vade mecum.

Assessment methods and criteria

A written exam on the subject defined by the professor and scientific staff : written exam.
Oral resit (first session only)in case of an insufficient score at the written exam.
The oral resit is subject to prior registration. Rejection criterion oral exam: too serious deficiency at the written exam.

Work placement(s)

Internship opportunity.
Student assistant: opportunities are given to students interested in teaching Analytical Chemistry. The work mainly consists of supervising practical exercises.
Research: outside class and exam periods (from the end of the second year of the Baccalaureat), students interested in Analytical Chemistry can participate in an internship in the laboratory (student-researchers). PhD degrees can subsequently be prepared in the department.

Organizational remarks

There is a forum "MyULg" where students can post questions about the subject matter.

Contacts

Philippe Hubert, Laboratory of Analytical Chemistry, Department of Pharmacy, CHU Bât. B36, Quartier Hôpital,avenue Hippocrate 15, 4000 Liège 1 Phone. : 04/366.43.16 (15) Fax : 04/366.43.17 e-mail: ph.hubert@ulg.ac.be
Hugues Jambo Tél : +32 4 366.43.19 e-mail : Hjambo@ulg.ac.be
Charlotte De Bleye Tél : +32 4 366.39.79 e-mail : cdebleye@ulg.ac.be
Eric Ziemons Phone: +32 4 366.98.01 e-mail : eziemons@ulg.ac.be
Secretary: Florence Bonivert Phone. : 04/366.43.16 Fax : 04/366.43.17 e-mail: florence.bonivert@ulg.ac.be

Introduction to pharmaceutical analytical chemistry