Duration
15h Th
Number of credits
| Master in bio-informatics and modelling (120 ECTS) | 2 crédits | |||
| Master in biochemistry and molecular and cell biology (120 ECTS) | 2 crédits |
Lecturer
Coordinator
Language(s) of instruction
French language
Organisation and examination
Teaching in the first semester, review in January
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
The course presents the various optical methods used in biochemistry. Spectroscopic methods taught in the course will be : UV-Visible absorption, linear and circular dichroïsmes, fluorescence, vibrational spectroscopy (eg. infrared and raman), surface plasmon resonance. For each method, principles, technical aspects and applications focused on biological macromolecules will be developed. The course will concludes with a review of the optical properties of proteins.
Learning outcomes of the learning unit
Increase the skills of the student regarding the available spectroscopic methods for the study of the conformational dynamics of biological macromolecules.
Prerequisite knowledge and skills
Basic chemistry and physics
Planned learning activities and teaching methods
Lectures are given with the help of powerpoint presentations, blackboard and chalk
Mode of delivery (face-to-face ; distance-learning)
Face-to-Face only
Recommended or required readings
Powerpoint presentations or lecture notes will be available following the lectures Reference books: - Biophysical Chemistry, Cantor and Schimmel - Principles of Physical Chemistry, Van Holde et al. - Biological Spectroscopy, Campbell and Dwek - Physical Biochemistry, Sheehan
Assessment methods and criteria
Student evaluation will be based on a written exam.
Work placement(s)
Non applicable
Organizational remarks
Lectures will be organized following the schedule known by the students. The professor will inform the students in advance of any possible modification to this
Contacts
Christian Damblon, Professor, Department of Chemistry, Institut de Chimie B6c, room 3/71, Allée de la Chimie, 3, University of Liège, B4000 Liège (Sart-Tilman), Tel.: +32 (0)4 3663788, Fax: +32 (0)4 3663413, E-mail: c.damblon@ulg.ac.be(P.Colson@ulg.ac.be; André Matagne, PhD, Professor, Enzymology and Protein Folding, Centre for Protein Engineering, Life Science Department, Institut de Chimie B6c, room 3/1, Allée de la Chimie, 3, University of Liège, B4000 Liège (Sart-Tilman), Tel.: +32 (0)4 3663419, Fax: +32 (0)4 3663396, Email: )amatagne@ulg.ac.be