2017-2018 / BIOC0002-2

Biochemistry

Duration

30h Th, 40h Pr

Number of credits

 Master in bio-informatics and modelling (120 ECTS)7 crédits 

Lecturer

Paulette Charlier

Language(s) of instruction

French language

Organisation and examination

Teaching in the second semester

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

Introduction to the chemistry of living organisms: structural and dynamic aspects.

Learning outcomes of the learning unit

General introduction to the properties of living matter at the molecular level. 1. Organic chemistry
2. Life strategy. The living cell.
3. Conservation and use of the genetic information. DNA, RNA and protein synthesis. Mutations, heredity and genetic engineering
4. Protein structure.
6. The functions of proteins.
7. Energy cycle. Energy and metabolism: glycolysis and photosynthesis.

Prerequisite knowledge and skills

General chemistry.
Chemical thermodynamics.

Planned learning activities and teaching methods

- Exercises : organic chemistry applied to living matter
- Tutorials dedicated to the Pymol software use: observation and analysis of biological macromolecules structures. Courses illustration. Use of PDB database.

Mode of delivery (face-to-face ; distance-learning)

15- 4hr periods each comprising 2 hrs of theory and 2hrs of practicals

Recommended or required readings

The PowerPoint presentations of the theoretical course will be available on CD as well as the notes of practical works.
Books recommended:
- "Biochimie générale" Auteur : Jacques-Henry WEIL Editeur : DUNOD Collection : Science sup Année: 07/2009 (11ème édition) - "Introduction to Protein Structure" Carl Branden and John Tooze, Garland Publishing 1999 CD roms: - PS ² and Kinemage Supplement to "Introduction to Protein Structure" Carl Branden and John Tooze, Garland Publishing 1999

Assessment methods and criteria

Written exam

Work placement(s)

Organizational remarks

15 - 4 hrs periodes with 2 hrs of theoretical course followed by 2 hrs of TP. TP is organized at building B37, room -1/45...

Contacts

Paulette Charlier, PhD, Chargé de Cours Cristallographie des macromolécules biologiques, Centre d'Ingénierie des Protéines, Département des Sciences de la Vie, Université de Liège, Institut de Physique, B5a, B-4000 Liège, Belgium Tel: +32 (0)4 366 36 19 Fax: +32 (0)4 366 49 54
E-mail : Paulette.Charlier@ulg.ac.be http://www.cip.ulg.ac.be/