General pathological anatomy

Duration

20h Th, 10h Pr, 7h SI

Number of credits

Lecturer

Philippe Delvenne

Language(s) of instruction

French language

Organisation and examination

Teaching in the second semester

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

The consequences of aggressions (stress) on cells and tissues are studied: reversible injury, cell death by necrosis, apoptosis or autophagy, tissue necroses, adaptation processes at the cell or tissue level, cell or tissue overloading.
Next, the subsequent reactions are discussed: inflammation, immunity, repair, healing.
The hypersensitivy reactions contribute to cell and tissue damage; some particular cases such as tuberculosis, graft rejection, auto-immune diseases are reviewed.
Vascular diseases as well as pathological conditions leading to thrombosis and embolism are studied and their consequences, ie. infarcts, are described.
The study of benign and malignant tumors include morphological features and biological properties as well as an overview on their etiology and pathogenesis.

Learning outcomes of the learning unit

Pathology is the study of diseases. The course of General Pathology aims at describing the lesions induced by aggressions and stress in cells and tissues as well as the reactions of the body. Besides, the course defines the aetiology and discusses the pathogenesis of the lesions.
General Pathology is complementary to Histology & Biochemical pathology and is the basis of comprehensive medicine; from aetiology to lesions through pathogenesis, this course introduces the study of the consequences of cell and tissue injury on the functions of the organs (physiopathology) and the expression of these consequences as diseases.

Prerequisite knowledge and skills

A good knowledge of the courses of Q2 and Q3 (particularly histology) is a prerequisite.

Planned learning activities and teaching methods

Practical courses: 1) at the microscope; two sessions of two hours (30 to 40 students) preceded by an explanation lecture. 2) on-line auto-evaluation (multiple choice questions, based on concrete cases). Modalities : Practical courses at the histology & pathology room (B36, niv -1, 4000 Sart Tilman); assistance mandatory and checked; no interrogation but appreciation on the participation to the evaluation on-line. A web site (http://www.anapatho.ulg.ac.be/) is also available for the students.

Mode of delivery (face-to-face ; distance-learning)

Ex cathedra lectures given in quadrimester 4. Dr M. HERFS, J. SOMJA and P. HUBERT participate to some lessons. Distance-learning for practical courses (partim)

Recommended or required readings

A syllabus and powerpoint presentations are available on MyULg. The syllabus is also available at AREM.
 Reference textbook: « Basic Pathology» par Kumar, Cotran et Robbins (Saunders Ed.)
 Other references:
-« Pathologic basis of diseases» by Cotran, Kumar et Collins (Saunders Ed.)
-Site WEB including pictures and comments on practical lesson slides, pedagogic objectives and examples of questions: http://www.anapatho.ulg.ac.be/
The textbooks are available for consultation at the Life Sciences Library of the University Hospital of Liège.

Assessment methods and criteria

See the file «modalité d'évaluation et de délibération»
Written examinations for the theorical and practical parts (multiple choice questions, open question with short answers). During the oral integrative examination, the students may be questioned on the general pathology course.

Work placement(s)

Organizational remarks

Some students may be selected to become "tutors" for other students at the practical courses. Conditions : good results at the examinations of Pathology (theory and practical lessons); good global results (grades); motivation.
Possibility to performe research (cancerogenesis, anti-tumor immunity,...). Conditions : good global results (grades); motivation.

Contacts

Secretariat: Melle M. BASIGLINI: relations with students for administrative problems. Adress : Anatomie Pathologique, Tour de Pathologie (1er étage), Sart Tilman Tel. : 04/366.24.10 E-mail: anacytopat@ulg.ac.be Coordinators of practical lessons: Docteur J. SOMJA & P. HUBERT Adress : Anatomie Pathologique, Tour de Pathologie (1er étage), Sart Tilman E-mail : Joan.Somja@ulg.ac.be p.hubert@ulg.ac.be
 (Joan.Somja@ulg.ac.be)

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