IMMU0120-6 : Multidisciplinary approach to the blood system

Study Programmes 2015-2016

IMMU0120-6

Multidisciplinary approach to the blood system

Duration :

12h Th

Number of credits :

Bachelor in medicine		3

Lecturer :

Philippe Kolh, Pascale Quatresooz

Language(s) of instruction :

French language

Organisation and examination :

Teaching in the first semester, review in January

Units courses prerequisite and corequisite :

Prerequisite or corequisite units are presented within each program

Course contents :

The module concerns the hematologic system. The lectures on normal and pathologic biochemistry and physiology encompass the following chapters:

Introduction
Erythrocytes

Generalities
Erythropoiesis
Vitamin B12
Specific metabolism of the erythrocytes
Glutathione
Erythrocytes degradation

Haemoglobin

Generalities
Molecular structure
Biosynthesis
Iron metabolism
Oxygen transport
CO2 transport
Haemoglobin as buffer
Inactive and abnormal haemoglobins
Haemoglobin degradation

Blood groups
Platelets
Haemostasis: biochemistry

Introduction
Components of primary haemostasis
The different steps of primary haemostasis
Components of secondary haemostasis
The different steps of secondary haemostasis
Fibrin degradation
Thrombin central role

Learning outcomes of the course :

The objective of the course is to master the principles of biochemistry and physiology of the hematologic system. It focuses on red blood cells, blood groups, and platelets. The learning outcomes are detailed under “contents of the course”

Prerequisite knowledge and skills :

General Biochemistry; General Physiology

Planned learning activities and teaching methods :

Lectures with active participation of students
Problems-based learning

Mode of delivery (face-to-face ; distance-learning) :

Face-to-face delivery; lectures are podcasted