Study Programmes 2015-2016
GBIO0031-1  
Learning from genomic data
Duration :
150h Proj.
Number of credits :
Master in biomedical engineering (120 ECTS)5
Master in biomedical engineering (120 ECTS)5
Master in computer science and engineering (120 ECTS)5
Master in computer science and engineering (120 ECTS)5
Master in computer science (120 ECTS)5
Master in computer science (120 ECTS)5
Lecturer :
Kristel Van Steen
Language(s) of instruction :
English language
Organisation and examination :
Teaching in the second semester
Units courses prerequisite and corequisite :
Prerequisite or corequisite units are presented within each program
Course contents :
Students are provided with an active research problem that requires carrying out a detailed genome-wide association interaction study (either population-based or family-based). This research problem is provided by the supervisor or via ongoing collaborative efforts.  
Depending on the nature of the data students may opt for parametric or non-parametric analysis methods, statistical or machine learning based analytic tools.
 
Given the interdisciplinary nature of the project work, students can work in groups of 2 or 3. Upon termination of the project, each individual prepares an individual report.  There are no class sessions apart from one during which the project problem is introduced. Theoretical and practical guidance is offered upon request.
Learning outcomes of the course :
Given data, students are able to apply and reinforce acquired knowledge on a practical problem in statistical genetics. In particular, students are able to carry out a sound and detailed genetic association interaction analysis, with the most appropriate software tool at hand, covering the following aspect from the analysis pipeline: data cleansing, statistical analysis, interpretation, reporting. 
Prerequisite knowledge and skills :
A background in biomedicine and/or informatics is a pro.
Planned learning activities and teaching methods :
During a kick-off meeting, the problem and data are introduced. Students can use their own data upon agreement with the course responsible. Students can work alone (discouraged) or in groups of maximum three students. Several groups may work on the same or different real-life data set (depending upon availability). Supervision is provided via members of the BIO3 group at the EECS department of the School of Applied Sciences. Group meetings with the supervisors may be organized upon request. Upon termination of the project, each individual prepares a report and orally defends it.
Mode of delivery (face-to-face ; distance-learning) :
Primarily distance learning
Recommended or required readings :
There is no mandatory textbook. Essential information will be posted on the websites
http://www.montefiore.ulg.ac.be/~kvansteen/ (theory)
http://www.montefiore.ulg.ac.be/~chaichoompu/CK/?Courses (practice)
Assessment methods and criteria :
Grading is based on a report and its oral defense using the following 5 criteria:
  • Ability to formulate the research problem and the context (introductions, data description)
  • Presentation of the analysis workflow (methods, analysis section)
  • Quality of the analysis (validity of results)
  • Creative input (analytic tool, stuffing, conclusion section)
  • Quality of the report and presentation slides
Work placement(s) :
Organizational remarks :
The project work is organized in the second semester.
Exam in June
 
Contacts :
Kristel Van Steen - e-mail kristel.vansteen@ulg.ac.be
Assistant: Kridsadakorn Chaichoompu -  e-mail kridsadakorn.cha@gmail.com
Preferred contact mode: e-mail or personal contact, after a lecture or by appointment