CHIM9239-2 : Chemistry of biological molecules

Study Programmes 2015-2016

CHIM9239-2

Chemistry of biological molecules

Duration :

36h Th

Number of credits :

Bachelor in bioengineering		3

Lecturer :

Aurore Richel

Language(s) of instruction :

French language

Organisation and examination :

Teaching in the second semester

Units courses prerequisite and corequisite :

Prerequisite or corequisite units are presented within each program

Course contents :

Carbohydrates : classification of carbohydrates, principal sugars and nomenclature, structure and conformation, chemical reactivity and physical properties, polysaccharides, applications. Lipids : nomenclature, chemical structure and physico-chemical properties, glycerides, unsaponifiable, application domains. Amino acids, peptides and proteins. Structure and principal properties. Exemple of protein structures (alpha-keratin, fibroïn, collagen, elastin). Protein denaturation mechanism and practical importance. Amino acids, peptides and proteins : Analysis, sequence, conformation, peptide synthesis, interactions, modifications, purification. Structure activitiy of proteins. Biomolecules analysis and purification methods. Precipitation, Partition, Ion exchange, Chromatography, Electrophoresis
Secondary metabolites
Application domains for biological chemistry - group presentation

Learning outcomes of the course :

To give basic knowledge in organic chemistry of natural molecules. To draw molecular and structural properties of biomolecules.Present analysis and purification methods for biomolecules. After completing the course the student is expected to be able to give back the basic knowledge of the three main groups of compounds from biological origin : protein, lipids and glucids, to demonstrate the convergence points with the cursus in organic chemistry and to point out the first applications of the teached topics.Understand the different principles of bio-molecules separation and be able to choose the right principle in function of the molecules to separate Understand the ionization phenomenon and predict the possible effect on association, biological activity.

Prerequisite knowledge and skills :

CHIM9268-1 - General chemistry CHIM9255-3 - Organic chemistry CHIM9267-1 Equilibrium chemistry

Planned learning activities and teaching methods :

Theoretical lectures.

Mode of delivery (face-to-face ; distance-learning) :

Lectures