Study Programmes 2015-2016
| BIOC0719-1 | ||||||||
| Enzymology | ||||||||
|
Duration :
|
||||||||
| 15h Th | ||||||||
|
Number of credits :
|
||||||||
|
||||||||
|
Lecturer :
|
||||||||
| André Matagne | ||||||||
|
Language(s) of instruction :
|
||||||||
| French language | ||||||||
|
Organisation and examination :
|
||||||||
| Teaching in the second semester | ||||||||
|
Units courses prerequisite and corequisite :
|
||||||||
| Prerequisite or corequisite units are presented within each program | ||||||||
|
Course contents :
|
||||||||
| Chapter 1: General properties of enzymes. Chapter 2: Steady-state kinetics. Chapter 3: Enzyme inhibition. Chapter 4: Effect of pH, temperature, viscosity and other experimental factors. Chapter 5: Reactions of two substrates. Chapter 6: Transient-state kinetics. Chapter 7: Cooperativity and allosteric interactions. Chapter 8: Enzyme inactivators. Chapter 9: Enzyme cofactors. Chapter 10: Mechanism of chymotrypsin. Chapter 11: Basic catalytic principles. Chapter 12: Regulation of catalytic activity. | ||||||||
|
Learning outcomes of the course :
|
||||||||
| The aim of the course is to make students familiar with both enzyme mechanisms and fundamentals of enzyme kinetics. | ||||||||
|
Prerequisite knowledge and skills :
|
||||||||
| Biochemistry course (BAC3), which includes an introduction to enzyme catalysis (chapters 1-3). | ||||||||
|
Planned learning activities and teaching methods :
|
||||||||
| Most lectures are given using the blackboard and (hopefuly) white chalk. | ||||||||
|
Mode of delivery (face-to-face ; distance-learning) :
|
||||||||
| Face-to-face only | ||||||||
|
Recommended or required readings :
|
||||||||
| Reference book: A. Cornish-Bowden, Fundamentals of enzyme kinetics, fourth edition, Wiley-Blackwell, 2012. | ||||||||
|
Assessment methods and criteria :
|
||||||||
| Oral exam | ||||||||
|
Work placement(s) :
|
||||||||
|
Organizational remarks :
|
||||||||
| The students will contact the professor asap in order to plan the course schedule | ||||||||
|
Contacts :
|
||||||||
| André Matagne, PhD, Professor, Enzymology and Protein Folding, Centre for Protein Engineering, Life Science Department, Institut de Chimie B6c (room 3/1), Allée de la Chimie, 3, University of Liège, B4000 Liège (Sart-Tilman), Tel.: +32 (0)4 3663419, Fax: +32 (0)4 3663396, Email: amatagne@ulg.ac.be | ||||||||