Study Programmes 2015-2016
ANIM0004-4  
Microbial biochemistry and physiology
Duration :
10h Th, 12h Pr
Number of credits :
Master in agricultural bioengineering (120 ECTS)2
Master in bioengineering : chemistry and bio-industries (120 ECTS)2
Lecturer :
Micheline Vandenbol
Language(s) of instruction :
French language
Organisation and examination :
Teaching in the second semester
Units courses prerequisite and corequisite :
Prerequisite or corequisite units are presented within each program
Course contents :
- Mating in yeast as model organism (sexual reproduction), physiological and molecular description, signal transmission, synthesis and maturation of pheromones ;
- Control of cell division cycle in yeast, cyclins, control of genome integrity and stability ;
- Isolation of ts mutants (temperature-sensitive mutants) and cdc mutants (cell division cycle) in microorganisms;
- Identification of genes that control cell, conservation of regulation process in Eukaryotes;
- Diversity of antimicrobial peptides from bacteria and description of their mechanisms of action;
- Description of some microbial metabolism (nitrogen and phosphate);
- Practical works: methods to measure different parameters of microbial metabolism.
Learning outcomes of the course :
- Overview of different biochemical and physiological mechanisms from different microbial cellular processes (intracellular transduction, cell division cycle control, nitrogen and phosphate metabolism) ;
- Overview of specialized methods developed to study the microbial metabolism.
After completing the course, the student is expected
- to understand the different aspects of the microbial metabolism and physiology
- to practice the appropriate techniques to study a particular metabolism.
Prerequisite knowledge and skills :
BIOL2013 - General microbiology
BIOL2015 - Molecular biology
Planned learning activities and teaching methods :
PowerPoint available on MyULg.
Mode of delivery (face-to-face ; distance-learning) :
Lectures : 10 h Practical Works : 12 h (obligatory)
Recommended or required readings :
- Microbiology (Prescott et al.), 2011, 8th edition, McGram-Hill Pub., London, 1088 pages + appendixes
- La levure (P. Thuriaux), 2004, Ed Belin, 282 pages
- The metabolism of Saccharomyces cerevisiae, 2004, Ed J.R. Dickinson, M. Schweizer
- Biologie moléculaire de la cellule (Lodish et al.), 2005, Ed. de Boeck
- Publications from recent literature.
Assessment methods and criteria :
Written examination (100%)
Work placement(s) :
Organizational remarks :
Contacts :
Vandenbol Micheline (Professeur ordinaire) Microbiologie et Génomique 081/622353
m.vandenbol@ulg.ac.be