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| PHAR2020-1 | Integrated practical work
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| Duration : | 40h Pr |
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| Number of credits : |
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| Lecturer : | Brigitte Evrard, Marianne Fillet, Pierre Francotte, Michel Frederich, Philippe Hubert, Géraldine Piel, Bernard Pirotte, Anne-Catherine Servais, Monique Tits, Eric Ziemons |
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Language(s) of instruction :
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| French language |
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Organisation and examination :
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| Teaching in the second semester |
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Course contents :
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| The integrated practical work, divided into 4 parts, includes 5 pharmaceutical fields: analytical pharmaceutical chemistry, analytical chemistry, medicinal chemistry, pharmacognosy and pharmaceutical technology. During this integrated practical work, the students will synthesize a chiral active compound and characterize it (particles size, nuclear magnetic resonance, enantiomeric purity using capillary electrophoresis). They will also produce pharmaceutical dosage forms containing synthetic or natural active substances (gastro-resistant capsules of acetylsalicylic acid, paracetamol tablets and thyme tincture-based syrup). These pharmaceutical dosage forms will then be characterized using pharmaceutical technical procedures (delayed-release, friability, disintegration, resistance to crushing, dissolution test ...) as well as different analytical methods in order to determine their qualitative and quantitative content (TLC, HPLC, GC, Raman and near-infrared spectroscopy). |
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Learning outcomes of the course :
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| · To offer the students a global view of a drug, from raw materials to finished products;
· To increase students awareness of their future responsibilities as health professionals on the quality of the drugs they will dispense. |
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Prerequisites and co-requisites/ Recommended optional programme components :
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| · Drug Analysis (PHAR0344-3)
· Analytical chemistry (CHIM0330-1 and CHIM0331-1)
· Medicinal chemistry (CHIM0332-2 and CHIM0333-2)
· Pharmacognosy (PHAR0331-3 and PHAR0332-2)
· Pharmaceutical technology and biopharmacy (PHAR0343-3) |
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Planned learning activities and teaching methods :
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Mode of delivery (face-to-face ; distance-learning) :
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| The integrated practical work will be organized on 5 consecutive days.
Attendance during practical work is mandatory. In case of justified non-attendance leading to an attendance rate below 90%, the teachers reserve the right to take any action they judge necessary in order to allow the students to catch up the session(s). |
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Recommended or required readings :
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| Written notes will be available on eCampus. |
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Assessment methods and criteria :
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| First session
Each part will give rise to a report, which will compile not only the obtained results but also answers to thought questions regarding the handling procedures and the used techniques.
Second session
The students will receive raw experimental data on the basis of which they will write a report compiling data handling and the answers to thought questions. |
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Work placement(s) :
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Organizational remarks :
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Contacts :
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