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| Version 2013-2014 |
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| METO0822-1 | Introduction to translational research
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| Duration : | 30h Th |
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| Number of credits : |
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| Lecturer : | Stéphane Berghmans, François Jouret |
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Language(s) of instruction :
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| French language |
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Course contents :
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| The "Introduction to Translational Research" is a 30-hour course spread over 15 x 2 hours.
Two professors share the teaching: Dr Stéphane Berghmans, VP Academic & Research Relations EU at Elsevier, and Dr François Jouret, nephrologist at Liège's CHU and postdoctoral specialist clinician at the FNRS. |
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Learning outcomes of the course :
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| The objectives of this 30-hour course entitled "Introduction to Translational Research" are:
- to present translational research tools, situated at the border between basic sciences and clinical sciences; and the world of research;
- introduce the broader horizon to which translational research and research in general belongss
- to explain the main experimental models of human diseases;
- to rationalise the choice of an animal model depending on the question asked and/or disease studied;
- to demonstrate the interest of translational research in understanding, diagnosing and treating human diseases;
- to remind students of the experimental and ethical limitations of translational research;
- to explain the difficulties of transposing some observations made in vitro and/or in vivo to man, and to identify the reasons why;
- place translational research in its legal and regulating frameworks;
- examine the science policy and the financing of translational research;
- the influence of lobbying, networking and management on translational research.
- to envisage the future of translational research, especially the position of bioinformatics.
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Prerequisites and co-requisites/ Recommended optional programme components :
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| Recommended optional programme components :
BIOL 2025-1
EPID 0430-1
NUTR 0718-1
QUAL 0438-1
SBIM 0451-1
SBIM 0451-2
SBIM 0477-1
SBIM 0481-2
SBIM 0492-1
TOXI 0441-1 |
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Planned learning activities and teaching methods :
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| The course will be taught as lectures, supported by PowerPoint-type slides. |
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Mode of delivery (face-to-face ; distance-learning) :
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| Face-to-face |
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Recommended or required readings :
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| Medical Physiology, 2e Updated Edition, by Walter F. Boron, Emile L. Boulpaep - Elsevier Ed.
The Immortal Life of Henrietta Lacks Paperback
by Rebecca Skloot - Crown Books Ed.
The American Journal of Translational Research, http://ajtr.org/
Improving your Research Management, by Alan M. Johnson - Elsevier Ed.
At the Helm, by Kathy Barker - CSHL Press |
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Assessment methods and criteria :
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| Written exam in the 1st session
Written exam in the 2nd session
At the end of this course, students will be able to:
- define the term "translational research" and describe the stages;
- understand the different applications of translational research;
- present a typical example of translational research in the fields of physiopathology, diagnosis and the treatment of human diseases;
- critically examine the limitations of translational research;
- understand the ethical stakes of translational research, both for animal models and the application to man of discoveries made in the laboratory;
- envisage the future challenges of translational research.
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Work placement(s) :
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| ./. |
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Organizational remarks :
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| Classes will be taught in English. |
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Contacts :
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| Dr François Jouret :
Francois.jouret@chu.ulg.ac.be
04/366.25.40
Dr Stéphane Berghmans,
s.berghmans@elsevier.com
+32 471.78.19.00 |
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