 | | |
| BIOC0724-1 | Chemistry of biological macromolecules
|
|
| Duration : | 20h Th |
|
| Number of credits : |
|
|
| Lecturer : | Moreno Galleni, André Matagne |
|
| Coordinator : | Moreno Galleni |
|
Language(s) of instruction :
|
| French language |
|
Organisation and examination :
|
| Teaching in the second semester |
|
Course contents :
|
| Editer
1) Chemical properties of amino acids and of the polypeptide chain
1.1 Nature of the polypeptide chain
1.2 Amino acids
1.3 Detection of aminoacids, peptides and proteins
1.4 Determination of the protein size
1.5 Determination of the aminoacid sequence
1.6 Chemical synthesis of peptides
1.7 Non ribosomal synthesis of peptides
1.8 Post transcription modification of the polypeptide chain
2) Mechanism of protein localization in prokaryotes and eukaryotes
3) Interactions affecting the properties of proteins
3.1 Nature of non covalent interactions
3.2 Intramolecular interactions
4) Conformational properties of proteins
4.1 Secondary and ternary structures of proteins
4.2 Spectroscopic properties od proteins in solution
5) Biophysical properties of soluble and membranar properties |
|
Learning outcomes of the course :
|
| The course will be devoted to the structural and chemical properties of proteins. |
|
Prerequisites and co-requisites/ Recommended optional programme components :
|
| Lectures in general biochemistry
Thermodynamic and classical physic
Organic chemistry |
|
Planned learning activities and teaching methods :
|
| The practical course (20 hours) will be devoted to the production and chaacterisation of a zinc beta-lactamase. |
|
Mode of delivery (face-to-face ; distance-learning) :
|
| 10 lessons of 2 hours |
|
Recommended or required readings :
|
| Syllabus + power point presentation |
|
Assessment methods and criteria :
|
| Written exam |
|
Work placement(s) :
|
| |
|
Organizational remarks :
|
| |
|
Contacts :
|
| Galleni Moreno, room 2/10, Institut de Chimie , B6a. Sart Tilman
Tel:04/3663549 - Fax:04/3663364 - Email:mgalleni@ulg.ac.be |
|
