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| BIOC0722-1 | Application of spectroscopic techniques to the study of folding and stability of proteins
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| Duration : | 20h Th, 10h Mon. WS |
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| Number of credits : |
| Master in Biomedicine, Research Focus, 1st year | | 2 |
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| Master in Biomedicine, Professional Focus in Quality Assurance, 1st year | | 2 |
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| Master in Biomedicine, Professional Focus in focus in cosmetology, 1st year | | 2 |
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| Master in Biomedicine | | 2 |
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| Master in Biochemistry and Molecular and Cell Biology, Research Focus, 1st year | | 3 |
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| Master in Biochemistry and Molecular and Cell Biology, Teaching Focus, 1st year | | 3 |
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| Master en biochimie et biologie moléculaire et cellulaire, à finalité spécialisée en bio-industrie, 1st year | | 3 |
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| Master in Biochemistry and Molecular and Cell Biology, Professional Focus in
Industrial Biochemistry, 1st year | | 3 |
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| Master en biochimie et biologie moléculaire et cellulaire, à finalité spécialisée en bioinformatique et modélisation, 1st year | | 3 |
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| Lecturer : | André Matagne |
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Language(s) of instruction :
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| French language |
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Organisation and examination :
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| Teaching in the second semester |
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Course contents :
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| This series of lectures is based on the use of biophysical methods (mainly optical spectroscopies, presented into details for course BIOC0721-1: Propriétés optiques des macromolécules biologiques) to study protein folding. Concrete examples (e.g. bêta-lactamases, single-domain antibody fragments, lysozymes) are analyzed in details, on the basis of theoretical background and data found in the literature. |
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Learning outcomes of the course :
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| Students will learn how biophysical methods can be used to study protein folding. |
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Prerequisites and co-requisites/ Recommended optional programme components :
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Planned learning activities and teaching methods :
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| Lectures are given with the help of powerpoint presentations, blackboard and white chalk |
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Mode of delivery (face-to-face ; distance-learning) :
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| Face-to-face only |
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Recommended or required readings :
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| Scientific articles will be given as they are analyzed and lecture notes will be available following the lectures |
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Assessment methods and criteria :
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| An oral will be organized. Each student is given ca. 30 min, with maximum 15 min for preparation and thus minimum 15 min for discussion. |
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Work placement(s) :
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Organizational remarks :
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| Lectures will be organized following the schedule known by the students. The professor will inform the students in advance of any possible modification to this |
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Contacts :
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| André Matagne, PhD, Professor, Enzymology and Protein Folding, Centre for Protein Engineering, Life Science Department, Institut de Chimie B6c (room 3/1), Allée de la Chimie, 3, University of Liège, B4000 Liège (Sart-Tilman), Tel.: +32 (0)4 3663419, Fax: +32 (0)4 3663396, Email: amatagne@ulg.ac.be |
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