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| INFO0098-1 | Introduction to the modeling of biological systems
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| Duration : | 25h Th, 25h Pr |
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| Number of credits : |
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| Lecturer : | Eric Bullinger |
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Language(s) of instruction :
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| French language |
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Organisation and examination :
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| Teaching in the first semester, review in January |
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Course contents :
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| The module will address the following topics:
- Motivate for quantitative & dynamical approaches in biology;
- Present mathematical modelling: advantages, limitations and facets;
- Introduce system properties such as stability, sensitivity and robustness;
- Biological examples from gene regulation and metabolism over intra and inter-cellular signalling to pharmacokinetics;
- Familiarise with systems biology approaches, challenges and computational tools.
The practical work on computer will utilize the following software:
- Cell Designer
- Copasi
- Matlab and the SBtoolbox2
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Learning outcomes of the course :
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| At the end of this module, the students will be able to:
- understand and exploit the theoretical and practical considerations of systems biology and mathematical modelling of biological systems;
- design and analyse mathematical models of biochemical reaction systems;
- demonstrate the ability to evaluate the benefits and disadvantages of a systems biology component in a research projet.
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Prerequisites and co-requisites/ Recommended optional programme components :
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| none |
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Planned learning activities and teaching methods :
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| The module is based on ex-cathedra lectures, exercises on paper and on a computer as well as a modelling and model analysis projet
This module is partly taught in English. Students may always ask questions in French or English. |
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Mode of delivery (face-to-face ; distance-learning) :
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| face-to-face |
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Recommended or required readings :
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| Recommended reading will be placed on the module's myulg pages. |
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Assessment methods and criteria :
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| Detailled individual report (publication style) on the project with a presentation (35%).
Oral exam (65%). |
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Work placement(s) :
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Organizational remarks :
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| The module will take place in the first quadrimestre at dates to be arranged. |
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Contacts :
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| E. Bullinger(E.Bullinger@ulg.ac.be
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Institut Montefiore, B28, I.128
Tel: +32 (0)4 366 - 26 77
E.Bullinger (at) ulg.ac.be(E.Bullinger@ulg.ac.be) |
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