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| CHIM0678-1 | Biochemistry
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| Duration : | 30h Th |
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| Number of credits : |
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| Lecturer : | André Matagne |
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Language(s) of instruction :
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| French language |
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Course contents :
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| Chapter I. Protein structure and function: I.1. Amino acids; I.2. Peptide bond; I.3. Non-covalent interactions; I.4. Secondary structure; I.5. Tertiary and quaternary structures; I.6. Fibrous and globular proteins; I.7. Protein folding. Chapter II. Basic concepts in Enzymology: II.1. General properties of enzymes; II.2. Enzyme kinetics : steady-state - independent binding sites; II.3. Enzyme inhibition; II.4. Catalytic strategies. Chapter III. Biological membranes: III.1. Membrane lipids; III.2. Lipid bilayers; III.3. Membrane proteins; III.4. Structure of membrane proteins. Chapter IV. Nucleic acid and the flow of genetic information: IV.1. Nucleotides; IV.2. DNA structure; IV.3. DNA replication; IV.4. Gene expression. Chapter V. Metabolism: V.1. Glycolysis and gluconeogenesis; V.2. Krebs cycle; V.3 Oxidative phosphorylation; V.4. Photosynthesis |
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Learning outcomes of the course :
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| The aim of these lectures is to teach students with fundamentals in biochemistry, i.e. 1) the structure of biological (macro)molecules, namely proteins, nucleic acids, lipids and carbohydrates; 2) their organization and function; 3) their metabolism. Emphasis will be given on the application of basic chemical principles in the life sciences. |
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Mode of delivery (face-to-face ; distance-learning) :
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| 30 hours of lectures, given with the help of powerpoint presentations, blackboard and white chalk |
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Recommended or required readings :
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| Lecture notes will be available following the lectures
Reference book:
Jeremy M. Berg, John L. Tymoczko and Lubert Stryer (2007) Biochemistry (2007), 6th edition, W.H. Freeman and Co., New York. |
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Assessment methods and criteria :
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| An oral exam will be organized |
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Contacts :
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| André Matagne, PhD, Professor, Enzymology and Protein Folding, Centre for Protein Engineering, Life Science Department, Institut de Chimie B6c (room 3/1), Allée de la Chimie, 3, University of Liège, B4000 Liège (Sart-Tilman), Tel.: +32 (0)4 3663419, Fax: +32 (0)4 3663396, Email: amatagne@ulg.ac.be |
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