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| BIOC0219-3 | Industrial biochemistry including biochemical engineering
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| Duration : | 24h Th |
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| Number of credits : |
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| Lecturer : | Michel Crine, Frank Delvigne |
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Language(s) of instruction :
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| French language |
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Course contents :
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| This course aims at presenting modelling princoples of biological reactors.
Concepts of biochemical engineering are first presented allowing the determination of mass balances in a biological reactor:
- Concept of ideal mixing stades and stationnay, discontinuous and fed-batch operating modes.
- Définition and use of kinetic parameters µ et Yxs.
- Establishment of mass balances for different operating modes of reactors.
The course then presents an analysis of interactions between physical mechanisms (hydrodynamics, mixing) and biological mechanisms:
- Analysis of this physico-biological interaction in order to direct bioreactor scale-up.
- Simulation of reactors and microbial reactions using MatLab (presentation of numerical algorithms used to solve differential equations).
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Learning outcomes of the course :
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| At the end of the course, students wil be able to model biological reactors at a macroscopic level and to made simulations using MatLab. They will also be able to detect physico-chemical parameters having the highest impact on reactor performance, depending on the investigated microbial process. |
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Prerequisites and co-requisites/ Recommended optional programme components :
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| Mathematics, Microbiology |
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Planned learning activities and teaching methods :
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| The course is based on ex-cathedra lectures and exercise presentation.
The ex-cathedra lectures are dedicated to the presentation of the fundamental concepts necessary for the analysis and mathematical representation of mass balances in a biological reactor.
Presented exercises are divided in two parts:
- modelling of industrial heterogeneous bioreactor.
- modelling of synthesis of recombinat protein by microbial cells.
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Mode of delivery (face-to-face ; distance-learning) :
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| Face-to-face |
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Recommended or required readings :
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| The course material is available on the eCampus website. |
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Assessment methods and criteria :
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| An written exam is organized during the first session (January).
Evaluation relies essentially on the understanding of concepts and relationships between them rather on the capacity to make restitution.
The exam proceeds with closed reference books.
The examination in August/September (retakes) is organized in the same way as in June. |
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Organizational remarks :
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| The course is organized during the first quadrimester. |
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Contacts :
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| Michel CRINE
Laboratoire de Génie chimique, B6c
e-mail : M.Crine@ulg.ac.be
Tél : 04.366.35.59
Frank DELVIGNE
Bio-industries, G1
e-mail : F.Delvigne@ulg.ac.be
Tél : 081.62.23.11 |
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