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| CHIM9255-1 | Organic Chemistry
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| Duration : | 28h Th, 44h Pr |
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| Credits/ECTS : |
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| Holder(s) : | Jean‑Paul Wathelet |
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| Language : | French language |
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| Course contents : | 1. Lectures:
1.1. Basic concepts:
Isomers, stereoisomers, Fischer and Newman projections, Cahn-Ingold-Prelog nomenclature. Covalence and polarisation, inductive and mesomeric effects.
1.2. Mecanism of the reactions:
Thermochemistry, electronic aspects (homolytic or heterolytic cleavages, carbocation and carbanion formation); stereochemical aspects; acidity, basicity, role of solvents.
1.3. Study of the main fonctional groups:
- Alkanes: free-radical substitution.
- Alkenes: electrophilic addition and anti-Markovnikov effect.
- Alkynes: electrophilic addition and nucleophilic attack; heavy metals
salts.
- Aromatic hydrocarbons: addition and substitution.
- Haloalkanes: SN1, SN2, E1, E2 mechanisms.
- Organometallic compounds: substitution, addition, reactions with labile H.
- Alcohols: reaction with bases and acids, esterification, dehydrogenation.
- Aldehydes et Ketones: substitution and nucleophilic addition.
- Amines: acidity-basicity, acylation, diazotization, reaction with carbonyl
groups.
- Carboxylic acids and derivatives: acidity-basicity, reduction,
decarboxylation. Nitrile hydrolysis, malonic synthesis, addition-
elimination for acyl halides.
2. Practical works:
2.1. Problems of nomenclature, determination of structure and synthesis
2.2. Experiences at the laboratory |
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| Course objective : | To ensure a basic training in organic chemistry for the future "Bio-Ingénieurs"; for "Bio-Ingénieurs" in Chimistry and Bioindustry, the course is the starting point of a teaching supplemented later on.
After completing the course the student is expected to
- to understand the bases of the organic chemistry
- to analyse the reactivity of the organic molecules
- to describe the mechanism of the chemical reactions
- to solve problems of organic chemistry (synthesis of organic molecules, determination of structure)
- to carry out some syntheses at the laboratory |
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| Prerequisites : | -- CG101 - General chemistry |
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| Organization : | Lectures : 28h
Practical Works : 44h |
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| Written notes : | Vollhardt-Schore: Traité de chimie organique; P.Arnaud: Chimie organique; Hart et Cornia: Introduction à la chimie organique; John McMurry: Chimie organique, les grands principes; J-P Wathelet: notes de cours |
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| Assessment : | Written examination (80%)
Group report (20%) |
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| Contacts : | Wathelet, Jean-Paul (Professeur, Responsable de l'Unité)
Chimie générale et organique
081 62 22 89
JP.Wathelet@ulg.ac.be |
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